Shanshan Deng

Overexpression of ONECUT1 suppresses hepatoblastoma progression via modulating tumor cell growth and tumor microenvironment

Yu Qiao, Meng Xu, Yanhui Wu, Guofei Cui et autres

BACKGROUND: Hepatoblastoma is the most common malignant liver tumor in children. Our previous work showed that enforced expression of the transcription factor One Cut Homeobox 1 (ONECUT1) suppresses the initiation of hepatoblastoma. However, it remains unclear whether increasing ONECUT1 expression can also …

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Biological treatments for zoonotic salmonellosis: an evolving therapeutic landscape

Sushan Ma, Xingmei Liu, Min Shen, Shanshan Deng et autres

Salmonellosis, a predominant food-borne gastroenteric disease, presents a substantial and escalating threat to global public health, largely attributable to infections by non-typhoidal Salmonella serovars such as Salmonella enterica serovar Typhimurium ( S. Typhimurium ) and Salmonella serovar Enteritidis ( S. Enteritidis ). …

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Anti‐mitotic agent SB‐216 overcomes taxane resistance in castration‐resistant prostate cancer and exhibits anti‐tumour efficacy in pancreatic cancer

Rui Wang, Chun Cai, Shanshan Deng, Yang Xie et autres

Abstract Background and Purpose The clinical success of small‐molecule drugs in treating pancreatic and prostate cancer patients has been both promising and challenging. Whereas patients with advanced‐stage tumours have significant initial responses to chemotherapy, many have experienced rapid resistance, metastasis and recurrence …

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Supplementary Figure S8 from Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

Guofei Cui, Yi Shi Zhou, Weiting Liao, Eleonora Cossu et autres

Unique pathways upregulated in Tsc2-/-/NRas and sgGSK3α/β/NRas liver tumors

Supplementary Table 1 from Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

Guofei Cui, Yi Shi Zhou, Weiting Liao, Eleonora Cossu et autres

Plasmid dosages used for HCC murine models

Supplementary Figure S9 from Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

Guofei Cui, Yi Shi Zhou, Weiting Liao, Eleonora Cossu et autres

Unique pathways downregulated in Tsc2-/-/NRas and sgGSK3α/β/NRas liver tumors

Supplementary Table 5 from Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

Guofei Cui, Yi Shi Zhou, Weiting Liao, Eleonora Cossu et autres

Primary antibodies information for Western blot analysis

Supplementary Table 2 from Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

Guofei Cui, Yi Shi Zhou, Weiting Liao, Eleonora Cossu et autres

Basic information of HCC murine models

Supplementary Table 4 from Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

Guofei Cui, Yi Shi Zhou, Weiting Liao, Eleonora Cossu et autres

Primary antibodies information for immunohistochemistry

Supplementary Table 6 from Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

Guofei Cui, Yi Shi Zhou, Weiting Liao, Eleonora Cossu et autres

RNA-seq sample information

Supplementary Table 3 from Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

Guofei Cui, Weiting Liao, Eleonora Cossu, Matthias Evert et autres

Main characteristics of the plasmids used in the experiments

Supplementary Figure S3 from Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma

Guofei Cui, Yi Shi Zhou, Weiting Liao, Eleonora Cossu et autres

Histology analysis of liver tissues from Akt/NRas and sgGSK3α/β/NRas mice