Sina Andalib

Quercetin-loaded cellulose nanofibers improve memory, learning, and attenuate endoplasmic reticulum stress in a rat model of Alzheimer’s disease

Mahdi Jalili, Parvin Babaei, Mostafa Golshekan, Mahmood Abedinzade et autres

Alzheimer's disease (AD) lacks effective disease-modifying therapy. This study evaluated the neuroprotective efficacy of quercetin-loaded cellulose nanofibers (QNP) in a streptozotocin (STZ)-induced AD rat model, focusing on memory impairment and endoplasmic reticulum (ER) stress. Forty-eight male Wistar rats were randomly allocated to …

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Brain penetration enhancer-based on amino acid prodrug self-assembling nanoparticles: a streamlined strategy for overcoming blood brain barrier

Nasim Shadmani, Zahra Karami, Hamideh Haghighat, Sina Andalib et autres

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Protective and therapeutic effects of betanin nanoparticles in an alzheimer’s rat model: modulation of behavior and expression of AQP4, BDNF, SIRT6, and Seladin-1

Nasim Abedimanesh, Seied Mehdi Miri, Ali Mohammadi, Fatemeh Shahmohammadi et autres

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Application of edaravone-loaded nanogel in alleviating behavioral deficits and oxidative stress in schizophrenia rat model

Sina Montazeri, Soroush Bijani, Hamid Rashidzadeh, Ali Ramazani et autres

Schizophrenia is considered as a main one of the public health issues, and imposes numerous burdens on patients and society. We previously reported, the pathophysiology of schizophrenia is influenced by inflammation and mitochondrial dysfunction. Edaravone (EDV) as a potent antioxidant with neuroprotective …

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Neuroprotective effect of rosuvastatin-loaded nanoemulsions against lipopolysaccharide-induced neuroinflammation and oxidative stress

Zahra Saberi, Neda Rostamkhani, Mohammadreza Saghatchi Zanjani, Maryam Salimi et autres

Neuroinflammation is a pathophysiological feature of several neurological disorders, including Parkinson’s disease, Alzheimer’s disease and traumatic brain injury, resulting from various intrinsic and environmental triggers. However, effective treatments are hindered by challenges in drug delivery to the central nervous system, primarily due …

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Electrospun silver chloride-loaded PVA nanofibers as a potential antibacterial and electroconductive scaffold for the management of wound infection and healing

Morteza Abazari, Ali Sharafi, Maryam Hassan, Hamid Reza Moghimi et autres

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Polydopamine contained hydrogel nanocomposites with combined antimicrobial and antioxidant properties for accelerated wound healing

Mahin Abdollahi, Sina Andalib, Roghayeh Ghorbani, Davood Afshar et autres

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Evaluation and Comparison of Fullerene (C60) Aqueous Suspension Administration Effects with Memantine HCL in Rat Model of Alzheimer’s Disease Considering Behavioral Patterns and Spatial Memory

Sina Andalib, Mehrnoosh Nikpour, Mehrdad Hamidi, Rafi Javadi et autres

: Alzheimer's disease (AD) is among the most prevalent neurodegenerative disorders leading to dementia in the elderly. The accumulation of amyloid-beta (Aβ) plaques and the formation of tau protein tangles are primary contributors to AD, which induce oxidative stress. Fullerene C60, a …

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Review of: "“Correlation does not Imply Causation”, while Psychotropic Drugs do cause Neurochemical Imbalances and Dysfunction of Neurotransmission"

Sina Andalib

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Influence of Poloxamer 188 on Anti-Inflammatory and Analgesic Effects of Diclofenac-Loaded Nanoemulsion: Formulation, Optimization and in Vitro/in Vivo Evaluation

Zahra Karami, Mohammadreza Saghatchi Zanjani, Sina Andalib, Hossein Babaie et autres

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Effect of Simvastatin and Low-Level Laser Therapy on Sutural Bone Formation After Expansion in Rats: Biomechanical, Computed Tomography and Immunohistochemical Assessment

Arash Farzan, Ali Moshiri, Sina Andalib, Mostafa Shamsi et autres

Introduction: The application of low-level laser therapy (LLLT) and some medications have been shown to accelerate bone formation in rapid palatal expansion (RPE). A combination of these two therapeutic modalities may reduce the time required for the retention period. This study sought …

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Clavulanic Acid: A Novel Potential Agent in Prevention and Treatment of Scopolamine-Induced Alzheimer’s Disease

Mahdieh Anoush, Zeinab Pourmansouri, Rafi Javadi, Benyamin GhorbanPour et autres

High Resolution Image Download MS PowerPoint Slide Background and Aim: Alzheimer’s disease (AD) is the most common form of dementia in the elderly. It is characterized as a multifaced disorder with a greater genetic contribution. The contribution of many genes such as …

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