Zhong Lin

Laparoscopic surgery for broad ligament adenomyoma: A case report and literature review

Lin Xiu, Yu-Jie Huang, Zhong Lin

RATIONALE: Adenomyoma of the broad ligament is rare. Owing to the absence of typical clinical signs and imaging methods, preoperative diagnosis is challenging, and it is mainly diagnosed through surgical pathology. PATIENT CONCERNS: The patient experienced recurrent lower abdominal pain for 4 …

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To explore the molecular mechanisms and shared genetic characteristics of rheumatoid arthritis and cervical cancer based on multiple omics and clinical samples

Xifeng Xu, Yujie Huang, Wei Wu, Zhong Lin et autres

OBJECTIVE: The potential association between rheumatoid arthritis (RA) and cervical cancer risk is still debated and necessitates additional clinical investigations. This study aimed to explore this relationship using Mendelian randomization and multi-omics analysis, aiming to enhance insights and reduce redundancy. METHODS: This …

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A Novel Nonsense Mutation in ARR4 Leads to X-linked High Myopia: A Genetic Paradox

Dejian Yuan, Tizhen Yan, Ning Tang, Shiqiang Luo et autres

ARR4 has been associated with X-linked, female-limited, high myopia. However, using exome sequencing (ES) in a Southern Chinese family, we identified the first hemizygous high myopia case in a male patient. A novel truncated mutation ( ARR4 : c.569C>G, p.S190*), which co-segregated …

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Meta-analysis of correlationship between HLA-G 3′UTR 14-bp Ins/Del polymorphism and virus susceptibility

Haiyan Lv, Huizhi Lv, Zhong Lin, Lihua Chen et autres

BACKGROUND: There is a considerable amount of literature on the potential relationship between human leukocyte antigen-G 14-bp Ins/Del polymorphism and virus infection; however, results from these studies were inconclusive. OBJECTIVES: A meta-analysis was carried out to determine whether the 14-bp Ins/Del polymorphism …

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Molecular diagnosis of yellow fever imported into Fujian province, 2016

Yuwei Weng, Jinzhang Wang, Yongjun Zhang, Ou JianMing et autres

Objective To make laboratorial diagnosis of imported yellow fever (YF) cases in Fujian province with molecular method . Methods Serum and urine samples were collected from suspected cases at various time-points post illness onset. Real-time RT-PCR and nested RT-PCR were performed respectively …

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The Polymorphism of XRCC3 Codon 241 and AFB1-Related Hepatocellular Carcinoma in Guangxi Population, China

Xi Dai Long, Yun Ma, De Ying Qu, Yun Guang Liu et autres

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