Accès ouvert
2023
other
OpenAlex
Steven L. Warner, Bret J. Stephens, Stanley Nwokenkwo, Galen H. Hostetter et autres
Abstract Purpose: The targeting protein for Xklp2 (TPX2) has recently gained attention as a putative oncogene possibly amplified in several human malignancies, including pancreatic adenocarcinoma. In this work, we sought to evaluate the copy number and expression of TPX2 in pancreatic cancer …
au, us
(code pays fourni par la source)
Accès ouvert
2023
other
OpenAlex
Steven L. Warner, Bret J. Stephens, Stanley Nwokenkwo, Galen H. Hostetter et autres
Abstract Purpose: The targeting protein for Xklp2 (TPX2) has recently gained attention as a putative oncogene possibly amplified in several human malignancies, including pancreatic adenocarcinoma. In this work, we sought to evaluate the copy number and expression of TPX2 in pancreatic cancer …
Accès ouvert
2023
supplementary-materials
OpenAlex
Steven L. Warner, Bret J. Stephens, Stanley Nwokenkwo, Galen H. Hostetter et autres
Supplementary Data from Validation of TPX2 as a Potential Therapeutic Target in Pancreatic Cancer Cells
Accès ouvert
2023
supplementary-materials
OpenAlex
Steven L. Warner, Bret J. Stephens, Stanley Nwokenkwo, Galen H. Hostetter et autres
Supplementary Data from Validation of TPX2 as a Potential Therapeutic Target in Pancreatic Cancer Cells
Accès ouvert
2009
article
OpenAlex
Steven L. Warner, Bret J. Stephens, Stanley Nwokenkwo, Galen H. Hostetter et autres
PURPOSE: The targeting protein for Xklp2 (TPX2) has recently gained attention as a putative oncogene possibly amplified in several human malignancies, including pancreatic adenocarcinoma. In this work, we sought to evaluate the copy number and expression of TPX2 in pancreatic cancer cell …
us
(code pays fourni par la source)
2007
article
OpenAlex
Stanley Nwokenkwo, Rubén M. Muñoz, Steven L. Warner, Haiyong Han et autres
C285 SMAD4 is an essential intracellular mediator of transforming growth factor-β (TGF-β) signaling and functions as a tumor suppressor. Inactivation of SMAD4 has been implicated in a number of tumor types, most notably in pancreatic cancers where SMAD4 is inactivated in 53% …
us
(code pays fourni par la source)
2007
article
OpenAlex
Steven L. Warner, Anastasia Sugeng, Bret J. Stephens, Stanley Nwokenkwo et autres
4959 Pancreatic cancer is the fourth leading cause of cancer death among men and women in the United States and novel approaches are urgently needed to combat this disease. The Targeting Protein for Xklp2 (TPX2) is a microtubule-associated protein whose gene is …
us
(code pays fourni par la source)
Accès ouvert
2006
article
OpenAlex
Steven E. Scherer, Donna M. Muzny, Christian Buhay, Rui Chen et autres
us, gb
(code pays fourni par la source)