Zecong Xiao

Triglyceride-Glucose Indices, Genetic Susceptibility, and Incident Dementia Risk Across Early CKM Syndrome Stages: A UK Biobank Prospective Cohort Study

Lin Zhu, Zecong Xiao, Jing Wang, Guo Xijie et autres

cn (code pays fourni par la source)

Correction to “Surgical Tumor-Derived Photothermal Nanovaccine for Personalized Cancer Therapy and Prevention”

Tan Li, Gengji Chen, Zecong Xiao, Bo Li et autres

Defect-engineered metal-organic framework as a universal platform for theranostic applications

Shuguang Yang, Xiaohong Xiong, Qiyu Zhong, Shiyun Xian et autres

cn (code pays fourni par la source)

Injectable hydrogel induces tumor cell extracellular calcification and bone regeneration to disrupt the osteolytic vicious cycle in bone metastasis

Minzhao Lin, Shaohui Deng, Simin Liang, Yujie Jiang et autres

bg, cn (code pays fourni par la source)

Corrigendum to “A dissolvable microneedle platform for the delivery of tumor-derived total RNA nanovaccines for enhanced tumor immunotherapy” [Acta Biomaterialia 2025, 199, 120-131]

Jiachen Wang, Sicong Huang, Huiye Wei, Simin Liang et autres

cn (code pays fourni par la source)

αPD-1-conjugated acid-cleavable nanodrugs overcomes cellular immunotherapy barriers in pancreatic tumors

Zhengkai Gan, Jing Huang, Minzhao Lin, Shaohui Deng et autres

Overcoming barriers in solid tumor immunotherapy remains challenging, with adoptive T cell therapies limited by antigen loss, poor tumor infiltration, and T cell exhaustion. Here, we present a nanoengineered tumor-infiltrating lymphocyte (TIL) therapy using anti-PD-1 antibody (αPD-1)-conjugated ZIF-8 nanoparticles to effectively suppress …

us, cn (code pays fourni par la source)

Tirzepatide retention in iWAT with mesoporous polydopamine encapsulation enhances weight loss through leptin receptor signaling

Lin Mi, Tan Li, Xiaoxin Xiang, Na Xiong et autres

INTRODUCTION: Tirzepatide (TZP), a dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor agonist, has been showing superior benefits in weight loss and glucose lowering in patients with obesity, while the tissue-specific mechanisms of TZP as well as its side effects remain to be …

cn, us (code pays fourni par la source)

Engineered peripheral CD4 T cells delivery across the BBB promote intracerebral Treg conversion unleashes microglial phagocytotic activity for Alzheimer's disease treatment

Zejie Zuo, Zecong Xiao, Liying Zhang, Shaohui Deng et autres

cn (code pays fourni par la source)

Engineering Mesenchymal Stem Cells with Antioxidant Catalase‐Loaded Metal–Organic Frameworks for Targeted Spinal Cord Injury Therapy

Shiyun Xian, Shuguang Yang, Zhouzhou Liao, Yujie Jiang et autres

Abstract Spinal cord injury (SCI) therapy is challenging because of the associated irreversible neurological deficits. These deficits are caused by primary damage and secondary pathological processes such as oxidative stress and inflammation. Although mesenchymal stem cells (MSC) demonstrate potential in SCI treatment …

cn (code pays fourni par la source)

Endothelia-targeting eye drops deliver a STING inhibitor to effectively reduce retinal neovascularization in ischemic retinopathy

Siying Wen, Xuemin He, Jiachen Wang, Zheyao Wen et autres

cn, cz, hk (code pays fourni par la source)

A dissolvable microneedle platform for the delivery of tumor-derived total RNA nanovaccines for enhanced tumor immunotherapy

Jiachen Wang, Sicong Huang, Huiye Wei, Simin Liang et autres

cn (code pays fourni par la source)

A PD‐L1 siRNA‐Loaded Boron Nanoparticle for Targeted Cancer Radiotherapy and Immunotherapy

Shaohui Deng, Lijun Hu, Guo Chen, Jujian Ye et autres

Abstract Although the combination of radiotherapy and immunotherapy is regarded as a promising clinical treatment strategy, numerous clinical trials have failed to demonstrate synergistic effects. One of the key reasons is that conventional radiotherapies inevitably damage intratumoral effector immune cells. Boron Neutron …

cn, us (code pays fourni par la source)