Svetlana V. Trushakova

Epidemic season 2023–2024: the palette of ARVI pathogens in some territories of the Russian Federation and WHO regions

Burtseva Ei, N. V. Breslav, Е. А. Мукашева, Kirill G. Krasnoslobodtsev et autres

The purpose of this work was to determine the characteristics of the circulation of acute respiratory viral infection (ARVI) pathogens during the epidemic season of 2023-2024 in the WHO regions and Russian Federation. MATERIALS AND METHODS: The article uses virological, immunological, and …

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Humoral and T-cell immune response against SARS-CoV-2 in children with acute respiratory infections

Svetlana I. Koteleva, О. П. Попова, Svetlana V. Trushakova, Ivan V. Kapustin et autres

Objective. The aim was to evaluate specific T-cell and antibodies against SARS-CoV-2 in children hospitalized with respiratory infectious diseases.Materials and methods. Examination of 121 children was carried out in 2021–2024. Among them 22% of patients were under 1 year of age, 33% …

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Analysis of the association of influenza clinical course with single nucleotide polymorphisms in genes affecting the interferon-λ3 production

Л. И. Николаева, Maya D. Stuchinskaya, Kristina P. Telepenina, Nadezhda G. Shevchenko et autres

Introduction. Predisposition to different courses of the infectious process is largely associated with the polymorphisms in human genome, especially in genes encoding proteins of the immune system. In the early stages of influenza infection such components of innate immunity as interferons I …

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Features of whooping cough in adolescents: clinical, diagnostic, and immunological aspects

О. П. Попова, Ju. V. Shvetsova, S. V. Bunin, I. M. Fedorova et autres

Objective. To analyze the clinical, diagnostic, and immunological characteristics of pertussis in adolescents. Patients and methods. The analysis is based on observations of 90 adolescents hospitalized in 2023–2024 with a diagnosis of pertussis. In 64 (71.1%) children, pertussis was observed in combination …

STUDYING THE ASSOCIATION OF ALLELIC VARIANTS OF THE GENES IFNL3 AND IFNL4 WITH COVID-19

Л. И. Николаева, Maya D. Stuchinskaya, Nadezhda G. Shevchenko, Kirill G. Krasnoslobodtsev et autres

The purpose of the work was to investigate the association of individual allelic variants of the polymorphic loci of genes IFNL3 (rs8099917 T/G) and IFNL4 (rs12979860 C/T) with the se-verity of COVID-19. No reliable association was found between individual allelic variants and …

Metapneumovirus infection in children in modern conditions: clinical and immunological parallels

О. П. Попова, Svetlana V. Trushakova, I. M. Fedorova, Svetlana I. Koteleva et autres

Aim. The study of metapneumovirus infection clinical and immunological features in children of different ages. Patients and methods. An analysis of 22 patients with mono-metapneumovirus infection is presented. There were 7 (31.8%) children under the age of 1 year, 8 (36.4%) — …

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Properties of influenza viruses that caused epidemic increases in morbidity in Russia and countries of the world during 2022–2023. The effectiveness of vaccine prophylaxis

Burtseva Ei, Ludmila V. Kolobukhina, Anna D. Panova, Е. А. Мукашева et autres

The purpose of this work was to determine the characteristics of the circulation of various viral respiratory pathogens during the epidemic season 2022–2023 against the background of the ongoing evolutionary variability of SARS-CoV-2. Materials and methods. The article uses methods used in …

Association of polymorphic variants of hemostatic system genes with the course of COVID-19

Л. И. Николаева, Maya D. Stuchinskaya, Anna V. Dedova, Nadezhda G. Shevchenko et autres

Introduction. COVID-19 is characterized by a varied clinical course. The aim of the work was to identify associations of SNPs of hemostatic system genes with COVID-19. Materials and methods. DNA was isolated from patients (n=117) and healthy participants (n=104). All infected patients …

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Epidemic season 2021–2022: Frequency of co-infection by respiratory viral pathogens

Burtseva Ei, Anna D. Panova, Ludmila V. Kolobukhina, Anna V. Ignatjeva et autres

BACKGROUND: This study was conducted to determine the characteristics of various viral respiratory pathogens spreading during the epidemic season 20212022 and the frequency of co-infection with SARS-CoV-2 and influenza. AIM: To assess the development of the influenza epidemic and frequency of cases …

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Features of the Circulation of ARVI Pathogens During of Emergence and Widespread of SARS-CoV-2 in the 2018–2021

Burtseva Ei, Л. В. Колобухина, Olga L. Voronina, Anna V. Ignatjeva et autres

Relevance. The long-term leadership of ARVI pathogens determines their significance in the damage caused to both health and the economy of the country. Aim. To identify the features of the structure of ARVI during the emergence and widespread spread of SARS-CoV-2. Materials …

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Clinical features of the course of Rhinoviral infection in children

О. П. Попова, R. V. Vartanyan, Svetlana V. Trushakova, S. V. Bunin et autres

Acute respiratory viral infections remain the most common diseases in the world, accounting for about 90% of all infectious diseases. The possibilities of etiological decoding of ARVI using modern examination methods made it possible to establish an increase in the proportion of …

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Peculiarities of the influenza and ARVI viruses circulation during epidemic season 2019–2020 in some regions of Russia

L'vov Dk, Burtseva Ei, Л. В. Колобухина, I. Т. Fedyakina et autres

INTRODUCTION: The surveillance of influenza viruses in ARVI structure and study of their properties in epidemic season 2019-2020 in Russian Federation are actual for investigations due to tasks of Global Influenza Strategy initiated by WHO in 2019. MATERIAL AND METHODS: The data …

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