Xiaopei Wu

Morphological and Molecular Evidence for Infrageneric Relationships in Blastus (Melastomataceae)

Xiaopei Wu, Li Wang, Zeng SiJin, Yan Deng et autres

Blastus Lour. is a taxonomically complex genus of Sonerileae (Melastomataceae), with unresolved infrageneric relationships and controversial boundaries among several species and varieties. In this study, we integrated morphological evidence with a broadly sampled internal transcribed spacer (ITS) dataset, an expanded nuclear ribosomal …

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Conductive silk fibroin-based hydrogel composite conduit with anti-inflammatory and anti-scarring properties for peripheral nerve regeneration

Liang Zhao, Xiaopei Wu, Peijun Xiong, Hanping He et autres

Peripheral nerve injury (PNI) remains a major clinical challenge because of the limited regenerative capacity of nerve tissue and the formation of an unfavorable inflammatory and fibrotic microenvironment after injury. In this study, a multifunctional conductive hydrogel-composite nerve conduit was developed by …

Conductive silk fibroin-based hydrogel composite conduit with anti-inflammatory and anti-scarring properties for peripheral nerve regeneration

Liang Zhao, Xiaopei Wu, Peijun Xiong, Hanping He et autres

Peripheral nerve injury (PNI) remains a major clinical challenge because of the limited regenerative capacity of nerve tissue and the formation of an unfavorable inflammatory and fibrotic microenvironment after injury. In this study, a multifunctional conductive hydrogel-composite nerve conduit was developed by …

Conductive silk fibroin-based hydrogel composite conduit with anti-inflammatory and anti-scarring properties for peripheral nerve regeneration

Liang Zhao, Xiaopei Wu, Peijun Xiong, Hanping He et autres

Peripheral nerve injury (PNI) remains a major clinical challenge because of the limited regenerative capacity of nerve tissue and the formation of an unfavorable inflammatory and fibrotic microenvironment after injury. In this study, a multifunctional conductive hydrogel-composite nerve conduit was developed by …

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Biodegradable 3D‐Printed Elastic Scaffolds With Bioactivity and Electro‐Mechanical Coupling Promote Neuro‐Vascularization for Critical‐Size Bone Defect Regeneration

Yuhao Xia, Yifu Zhu, Wenying Wei, Mengjiao Shi et autres

ABSTRACT The intrinsic electrophysiological properties of native bone tissue promote bone healing, highlighting the significant role of piezoelectric biomaterials in neuro‐vascularized bone regeneration. However, challenges remain with existing piezoelectric biomaterials regarding biodegradability, bioactivity, and structural stability. In this study, a 3D‐printed elastic …

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Style Length in Wild Rhododendron: From Cryptic Genetic Variation to Efficient Genome Prediction Strategy

Qirui Liu, Tingting Hang, Qiannan Ye, Zhenzhen Wu et autres

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A New Potential Biomarker for Strychnine Misuse in Human Urine Using Quadrupole‐Orbitrap LC–MS/MS

陆江海, Jiarui Wang, Xuxiao Zhao, Qiaoling Fei et autres

In this study, we investigate the metabolic profile of strychnine in human urine following controlled administration using liquid chromatography-quadrupole-Orbitrap mass spectrometry. A total of 25 metabolites were characterized and identified. These included 21 previously unreported and 4 previously reported metabolites. Four unreported …

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Electroactive Dual‐Drug Hydrogel‐ PLA Conduit for Nerve Regeneration

Kebi Li, Xiaopei Wu, Peijun Xiong, Hanping He et autres

Peripheral nerve injury (PNI) remains a major clinical challenge due to the limitations of autologous nerve grafting. Herein, a multifunctional composite nerve conduit was developed by integrating an oriented collagen-grafted polylactic acid (PLA) electrospun scaffold with a conductive and anti-inflammatory hydrogel to …

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A single-component photocurable chitosan hydrogel mitigates inflammation and promotes angiogenesis and neurogenesis for diabetic wound healing

Kun Liu, Dong Zhang, Changjiang Liu, Haifei Kang et autres

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AI-based prediction and validation in zebrafish model elucidates potential bioactivity of novel thiazolone derivative

Jiahui Cheng, Tingyuan Zheng, Tao-Yan Lin, Zhao Zhang et autres

The multifactorial etiology of age-related complex diseases, including Alzheimer's disease (AD), cancer, and type 2 diabetes mellitus (T2DM), challenges the efficacy of single-target therapeutics. The development of multi-target-directed ligands (MTDLs) represents a promising strategy to address these overlapping pathological networks. In this …

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Porous Si3N4 ceramics with high-performance thermal insulation and dielectric properties via gel casting and using pore-forming agents

Jianhua Zhang, He Lin Yang, Wei Wu, Xiaopei Wu et autres

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A spatiotemporally programmed bilayer coating for immunomodulatory and osteogenic enhancement of artificial ligament-bone integration

Tianwu Chen, Shuang Wang, Wei Wu, Jiawei Liu et autres

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