Phillip R. Bennett

The vaginal microbiota varies by self-identified ethnicity and HIV status throughout pregnancy and relates to preterm birth risk in a United Kingdom observational cohort

Emily Watters, Rachael Quinlan, Ann Smith, Heather Ferguson et autres

gb (code pays fourni par la source)

LACTIN-V (Lactobacillus crispatus CTV-05) leads to microbial and immune modulation in pregnant women at risk of spontaneous preterm birth:FLIP-1 study

Lynne Sykes, Ryan Laurence Love, Erna Bayar, Katia Capuccini et autres

gb, us, fr (code pays fourni par la source)

Microbiome preterm birth DREAM challenge: Crowdsourcing machine learning approaches to advance preterm birth research

Jonathan L. Golob, Tomiko Oskotsky, Alice Tang, Alennie Roldan et autres

Extracellular Vesicles From M1 and M2 Macrophages Elicit Sexually Dimorphic Responses in the Human Placenta

Paschalia Pantazi, Toby Clements, Harriet T. Parsons, Phillip R. Bennett et autres

gb, us (code pays fourni par la source)

ABO blood group antigens influence host–microbe interactions and risk of early spontaneous preterm birth

Katherine E Mountain, David Alan MacIntyre, Yun Sok Lee, Virginia Tajadura‐Ortega et autres

The mechanisms by which vaginal microbiota shape spontaneous preterm birth (sPTB) risk remain poorly defined. Using electronic clinical records data from 74,913 maternities in conjunction with metaxanomic (n = 596) and immune profiling (n = 314) data, we show that the B …

gb, au (code pays fourni par la source)

Evaluating Urine Protein-creatinine Ratio in Snakebite Patients and Its Relationship to Clinical Outcomes: An Observational Study

Phillip R. Bennett, K Dhilipan, M Boopathi

Background: Snakebite envenomation, particularly from haemotoxic and myotoxic species, such as Russell's viper and saw-scaled viper, poses a significant public health challenge in tropical and subtropical regions.Acute kidney injury (AKI), a common and life-threatening complication of snakebites, is associated with tubular and …

in (code pays fourni par la source)

Multi-omic analysis of vaginal bacteria:host immune and metabolic interactions in adverse early pregnancy outcomes

S. Bobdiwala, Pamela Pruski, Gonçalo dos Santos Correia, Maya Al‐Memar et autres

ABSTRACT Accurate and timely diagnosis of early pregnancy outcomes remains a clinical challenge, particularly in cases classified as pregnancy of unknown location, where ultrasound fails to confirm the location of the pregnancy. Delayed diagnosis can lead to serious complications, especially in ectopic …

gb, be, au (code pays fourni par la source)

DIGITAL TRANSFORMATION IN HIGHER EDUCATION: A BLEND OF SOCIAL SCIENCE, MANAGEMENT, AND POLICY PERSPECTIVES

Ponnusamy Munusamy Anbarasan, Phillip R. Bennett, Prem Shankar Gupta, Sharada Prasanna Rout et autres

The digital transformation of higher education represents a profound paradigm shift, moving beyond the mere digitization of existing practices towards a fundamental redesign of the educational model. This evolution has a long history, beginning with correspondence courses and evolving through radio, television, …

in (code pays fourni par la source)

Predictive value of cervical length for spontaneous preterm birth in women with cervical cerclage

Katherine E Mountain, S. Ng, Tania Elger, H. Judah et autres

OBJECTIVE: Cervical cerclage is an important treatment used to prevent spontaneous preterm birth (sPTB), but it is not universally successful. Understanding the factors associated with cerclage treatment failure may lead to improved patient selection and better patient outcomes. The objective of this …

gb (code pays fourni par la source)

Stalling of the endometrial decidual reaction determines the recurrence risk of miscarriage

Joanne Muter, Chow‐Seng Kong, M. A. Sonia Mollá Nebot, Maria Tryfonos et autres

In every menstrual cycle, progesterone acting on estrogen-primed endometrium elicits an inflammatory decidual reaction, rendering it poised for embryo implantation and transformation into the decidua of pregnancy. Here, we show that the sequential functions of the decidual reaction—implantation and decidualization—pivot on the …

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Identification and characterisation of vaginal bacteria-glycan interactions implicated in reproductive tract health and pregnancy outcomes

Virginia Tajadura‐Ortega, Wengang Chai, Lauren A. Roberts, Yibing Zhang et autres

Lactobacillus displacement from the vaginal microbiome associates with adverse health outcomes and is linked to increased risk of preterm birth. Glycans mediate bacterial adhesion events involved in colonisation and infection. Using customised glycan microarrays, we establish glycan interaction profiles of vaginal bacteria …

gb, pt, cn, ru, au (code pays fourni par la source)

O-078 CD138 expression in the endometrium associates with endometrial timing and inflammatory status but not microbiota composition: a translational analysis of the CERM trial

Joshua Odendaal, Katherine J. Fishwick, Gonçalo dos Santos Correia, Y Lee et autres

Abstract Study question To understand the relationship between endometrial CD138 expression and the reproductive tract microbiota. Summary answer CD138+ staining of endometrium is associated with general delay in endometrial maturation but not the composition of the microbiota. What is known already Chronic …

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