M. Maletić

A Novel Hybrid Adsorbent Based on Fly Ash and Waste Flax Fibers for Efficient Separation of Rare Earth Ions from Water

Tijana Radojičić, Katarina Trivunac, M. Maletić, Ivona Janković-Častvan et autres

In this study, carbonaceous and hybrid adsorbents were synthesized from waste flax fibers and fly ash, integrating two abundant waste streams into a single functional material. Materials were thermally modified and activated with NaOH at 500 °C in a nitrogen atmosphere. The …

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Environmental impact and bioavailability of metals in soils near an old slag disposal site

Igor Kodranov, Milica Vasić, M. Maletić, Ljiljana Tolić Stojadinović et autres

Rapid industrialization and economic progress provide numerous benefits to society, but they can also result in negative environmental impacts. Activities related to industrial production, including emissions, waste disposal, material storage, and transport operations, can contribute to the release of heavy metals into …

Mosaic human cortical organoids model mTOR-related focal cortical dysplasia through DEPDC5 loss-of-function

M. Maletić, Sara Bizzotto, Théo Ribierre, Kenza Guerdoud et autres

Abstract Focal cortical dysplasia type II (FCDII), a leading cause of pediatric drug-resistant focal epilepsy, results from brain somatic variants in genes of the mTOR pathway, including germline and somatic second-hit loss-of-function variants in the mTOR repressor DEPDC5 . Here, we investigated …

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Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy

Théo Ribierre, Alexandre Bacq, Florian Donneger, Marion Doladilhe et autres

Abstract Cortical malformations such as focal cortical dysplasia type II (FCDII) are associated with pediatric drug-resistant epilepsy that necessitates neurosurgery. FCDII results from somatic mosaicism due to post-zygotic mutations in genes of the PI3K-AKT-mTOR pathway, which produce a subset of dysmorphic cells …

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Modélisation de la dysplasie corticale focale et de l'épilepsie liées aux mutations de DEPDC5 dans les organoïdes corticaux

M. Maletić

Les mutations germinales hétérozygotes 'perte de fonction' de DEPDC5, un répresseur du complexe mTORC1, sont une des causes majeures d’épilepsies infantiles associées à une dysplasie corticale focale de type II (DCFII). Une deuxième mutation somatique sur l'allèle fonctionnel, appelé ‘second-hit’, est souvent …

Cortical organoid model of DEPDC5-related focal cortical dysplasia and epilepsy

M. Maletić

Modélisation de la dysplasie corticale focale et de l'épilepsie liées aux mutations de DEPDC5 dans les organoïdes corticaux Les mutations germinales hétérozygotes 'perte de fonction' de DEPDC5, un répresseur du complexe mTORC1, sont une des causes majeures d’épilepsies infantiles associées à une …

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Crystal Structure of mPGES-1 bound to DG-031

Jianwei Ho, M.R. Lee, Christian Rauch, Kristen Aznavour et autres

Crystal Structures of FLAP bound to DG-031

Jianwei Ho, M.R. Lee, Christian Rauch, Kristen Aznavour et autres

PRIMENA HORMONA U INDUKCIJI I SINHRONIZACIJI ESTRUSA I OVULACIJE KOD KRAVA

Voja Pavlović, M. Maletić, Slobodanka Vakanjac, Marko Pavlović et autres

Imajući u vidu značaj i obim stočarske proizvodnje, nameće se pitanje praćenjazdravlja i plodnosti u zapatima krava. Visoka produktivnost povlači za sobomnegativne efekte na plodnost, pa tako između proizvodnje mleka i plodnosti postoji„borba za primat”. Jedan od načina borbe za što bolju …

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Bovine foetal sex determination—Different DNA extraction and amplification approaches for efficient livestock production

Marko Ristanić, Lj Stanisic, M. Maletić, Uroš Glavinić et autres

Foetal sex determination using polymerase chain reaction (PCR) in mammals is based on the amplification of gender-specific foetal DNA sequences circulating in maternal blood. The bovine synepitheliochorial placenta does not allow a direct contact between the trophoblast and the maternal blood, resulting …

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Efficiency evaluation of a bivalent vaccine in the prophylaxis of mastitis in cows

Vladimir Magaš, Slobodanka Vakanjac, Vojislav Pavlovic, Branko Velebit et autres

Mastitis in cows represents one of the most actual problems in intensive dairy production. The longtime different approaches to the treatment of mastitis have not offered a suitable solution, and the problem of mastitis is still present and acute. Prevention of pathogen …

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Blood calcium level, liver and muscle function parameters in downer cow syndrome.

N. Tešic, D. Gvozdić, Dragan Vuković, Ivana Jovanović et autres