Nicola Stagnaro

Development and validation of a deep learning model for radiographic classification of pediatric femoral neck fractures

Wentao Wang, Shenghua He, Lihong Ou, Federico Canavese et autres

BACKGROUND: The Delbet-Colonna (DC) classification guides treatment of pediatric femoral neck fractures (PFNFs) but relies on clinical experience. No deep learning (DL) model has been developed and validated to differentiate between PFNFs and proximal femoral growth plates (PFGPs) and classify PFNFs via …

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Synchronous Cardiac Fibroma and Medulloblastoma in Gorlin Syndrome: A Paradigmatic Case and Narrative Review

Marta Molteni, Gianluca Trocchio, Antonio Verrico, Maria Derchi et autres

BACKGROUND: Gorlin syndrome (GS) is a rare autosomal dominant disorder, associated with pathogenic PTCH1 or SUFU variants, predisposing to tumors such as basal cell carcinoma, medulloblastoma (MB), odontogenic keratocyst, and, rarely, cardiac fibroma (CF). MB occurs in ~5% of GS cases, typically …

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Pediatric tracheal surgery: indications, complications and results

Martina Monti, Vittorio Guerriero, Roberto D’Agostino, Oliviero Sacco et autres

BACKGROUND: Pediatric tracheal surgery includes several complex and rare procedures. We report the surgical experience at our center. METHODS: Our center has multidisciplinary team manages laryngotracheal malformations. We retrospectively analyzed all tracheal surgeries from January 2009 to September 2023, excluding endoscopic cases …

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A complex foregut malformation: case report and review

Liliana Piro, Arianna Roggero, Nicola Stagnaro, Valerio Gaetano Vellone et autres

Introduction: Esophageal duplication cysts (EDCs) associated with pulmonary sequestration (PS) are rare congenital anomalies originating from the embryonic foregut. They often present diagnostic challenges due to their complex nature and non-communicating features. Case Report: We report the case of a one-year-old girl …

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Recommendations for cardiovascular magnetic resonance and computed tomography in congenital heart disease: a consensus paper from the CMR/CCT Working Group of the Italian Society of Pediatric Cardiology and the Italian College of Cardiac Radiology endorsed by the Italian Society of Medical and Interventional Radiology (Part II)

Pierluigi Festa, Luigi Lovato, Francesco Bianco, Annalisa Alaimo et autres

Cardiovascular magnetic resonance (CMR) and computed tomography (CCT) are advanced imaging modalities that recently revolutionized the conventional diagnostic approach to congenital heart diseases (CHD), supporting echocardiography and often replacing cardiac catheterization. This is the second of two complementary documents, endorsed by experts …

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Sternal cleft and pectus excavatum: an overlooked congenital association?

Liliana Piro, Federica Lena, Arianna Roggero, Nicola Stagnaro et autres

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Impact of 4D-Flow CMR Parameters on Functional Evaluation of Fontan Circulation

Lamia Ait-Alì, Nicola Martini, Elisa Listo, Elisa Valenti et autres

Abstract We sought to evaluate the potential clinical role of 4D-flow cardiac magnetic resonance (CMR)-derived energetics and flow parameters in a cohort of patients’ post-Fontan palliation. In patients with Fontan circulation who underwent 4D-Flow CMR, streamlines distribution was evaluated, as well a …

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Overcoming Underpowering in the Outcome Analysis of Repaired—Tetralogy of Fallot: A Multicenter Database from the CMR/CT Working Group of the Italian Pediatric Cardiology Society (SICPed)

Lamia Ait-Alì, Benedetta Leonardi, Annalisa Alaimo, Giovanna Baccano et autres

Background: Managing repaired tetralogy of Fallot (TOF) patients is still challenging despite the fact that published studies identified prognostic clinical or imaging data with rather good negative predictive accuracy but weak positive predictive accuracy. Heterogeneity of the initial anatomy, the surgical approach, …

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Comparison of 2D and 4D Flow MRI Measurements for Hemodynamic Evaluation of the Fontan Palliation

Elisa Listo, Nicola Martini, Stefano Salvadori, Elisa Valenti et autres

Background: The assessment of Fontan circuit’s flow is traditionally evaluated by multiple through-plane phase-contrast MRI acquisitions (2D flow), while recently, a single volumetric 4D-flow MRI acquisition is emerging as a comprehensive tool for the hemodynamic evaluation in congenital heart diseases. Purpose: To …

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Lateral Thoracic Expansion for Jeune's Syndrome, Surgical Approach, and Technical Details

Federica Lena, Liliana Piro, Valentina Forlini, Vittorio Guerriero et autres

INTRODUCTION: Jeune's syndrome, or asphyxiating thoracic dystrophy (ATD), is a rare autosomal recessive disorder characterized by skeletal dysplasia. Ribs are typically short and horizontal resulting-in lethal variant-in severe lung hypoplasia, progressive respiratory failure, and death. Lateral thoracic expansion (LTE) consists in staggered …

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Long term follow-up in two siblings with Sengers syndrome: Case report

Chiara Panicucci, Maria Cristina Schiaffino, Claudia Nesti, Maria Derchi et autres

BACKGROUND: Sengers syndrome is characterized by congenital cataract, hypertrophic cardiomyopathy, mitochondrial myopathy, and lactic acidosis associated with mutations in AGK gene. Clinical course ranges from a severe fatal neonatal form, to a more benign form allowing survival into adulthood, to an isolated …

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Long-Term Cardiovascular Outcome in Children with MIS-C Linked to SARS-CoV-2 Infection—An Italian Multicenter Experience

Nicoletta Cantarutti, Virginia Battista, Nicola Stagnaro, Marianna Eleonora Labate et autres

MIS-C is a multisystem inflammatory syndrome that is characterized by multi-organ failure and cardiac involvement. The aim of this study was to describe the long-term cardiovascular outcome in a cohort of MIS-C pediatric patients, who were admitted to two Italian Pediatric Referral …

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