Geeta K. Swamy

Association between breastfeeding and neurodevelopmental outcomes after late preterm birth

Geeta K. Swamy, Cynthia Gyamfi‐Bannerman, Torri D. Metz, Kent D. Heyborne et autres

Objective To test the hypothesis that breastfeeding is associated with improved neurodevelopmental outcomes among children delivered late preterm. Study design Secondary analysis of a prospective, follow‐up study of ≥6‐year‐old children enrolled in the Antenatal Late Preterm Steroid (ALPS) Trial, a multicenter study …

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Maternal Antibodies to Primary CMV Infection Link to Fetal Transmission

Chelsea M. Crooks, Richard Barfield, Adelaide S. Fuller, Brenna L. Hughes et autres

BACKGROUND Human cytomegalovirus (HCMV) is the leading global infectious cause of birth defects. Despite its prevalence as a cause of life-long disabilities, there are no licensed vaccines to prevent congenital CMV (cCMV), and correlates of protection remain poorly understood. To address this, …

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Association between breastfeeding and neurodevelopmental outcomes after late preterm birth

Anna Palatnik, Jessica de Voest, Alan T. N. Tita, Sean C Blackwell et autres

Objective: To test the hypothesis that breastfeeding is associated with improved neurodevelopmental outcomes among children delivered late preterm. Study design: Secondary analysis of a prospective, follow-up study of ≥6-year-old children enrolled in the Antenatal Late Preterm Steroid (ALPS) Trial, a multicenter study …

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Child Neurodevelopmental Outcomes After Late Preterm Hypoglycemia

Cynthia Gyamfi‐Bannerman, Jessica A. de Voest, Alan T N Tita, Sean C. Blackwell et autres

OBJECTIVE: To evaluate whether hypoglycemia in neonates born to mothers at risk for late preterm delivery was related to adverse effects on childhood neurodevelopment. METHODS: This was a prospective follow-up study of children aged 6 years or older whose mothers were enrolled …

Neonatal Inflammatory Profiles Associated With Perinatally Acquired Hepatitis C Viral Infection

Stephanie A. Fisher, Grecio J. Sandoval, George R. Saade, Brenna L. Hughes et autres

In this nested case-control study of infants with in utero hepatitis C exposure, we assessed 21 plasma cytokines/chemokines at age 2 months in 11 infants with perinatal transmission and 11 negative controls. Of 6 detectable biomarkers, cases exhibited higher plasma programmed death-ligand …

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Increased dose of H1N1 pandemic influenza vaccine during pregnancy improves immunity in mothers and infants

Dhvanir Kansara, Martina Košíková, Patricia L. Milletich, Jie Zhou et autres

Maternal-infant immunity against influenza is improved through vaccination during pregnancy. We conducted an in-depth analysis of antibody (Ab) responses in sera from pregnant and non-pregnant women immunized with an unadjuvanted inactivated influenza A (H1N1) monovalent vaccine during the 2009 pandemic (NCT00992719). Pregnant …

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Creating a responsible authorship culture in science: Anchoring authorship practices in principles of transparency, credit, and accountability

Véronique Kiermer, Sofia Adams, Kirsten Bibbins-Domingo, Yensi Flores Bueso et autres

Authorship remains the primary currency of academic credit and a cornerstone of research integrity, yet current practices often fail to reflect the collaborative and interdisciplinary nature of modern science and questionable authorship practices persist. We argue that addressing these shortcomings is a …

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Prediction of Hepatitis C Virus Perinatal Transmission in Pregnant Individuals With Hepatitis C Virus Infection.

Edward K. Chien, Brian M. Casey, George R Saade, Rebecca G Clifton et autres

Our objective was to develop a prediction model for hepatitis C virus (HCV) infection perinatal transmission to improve triage for neonatal follow-up. This was a secondary analysis of HCV antibody-positive participants who were enrolled in the Eunice Kennedy Shriver National Institute of …

Pregnancy outcomes among medically complex populations with high risk of pregnancy mortality in Virginia: a retrospective observational study

Michael J. Green, L. E. Anderson, Jerome Jeffrey Federspiel, Laura Kmitch et autres

BACKGROUND: Abortion may be medically indicated to avert death or permanent harm of the pregnant person. However, some US states now prevent access to abortion for these patients. To evaluate the population for whom this may cause harm, we aimed to estimate …

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Evaluation of Azithromycin Disposition in Pregnant Women Undergoing Cesarean Delivery – A Population-Based PBPK Modeling Approach

Peizhi Li, Kenan Gu, Geeta K. Swamy, Brenna Hughes et autres

Objectives: Cesarean delivery leads to surgical site infections (SSI) in ~5% of cases[ 1], with higher risks for obese pregnant women[ 2]. While cefazolin remains the standard prophylactic antibiotic, its coverage is limited. Azithromycin offers broader antimicrobial coverage as an adjunct therapy, …

Assessing the Association Between Perceived Discrimination in Health Care and Postpartum Contraception

Jonas J. Swartz, Tracy Q.S. Truong, Catherine Gervais, Evan R. Myers et autres

Objectives: To assess the association between perceived discrimination in health care and postpartum contraceptive plans among a diverse group of postpartum individuals. Materials and Methods: This was a cross-sectional study of individuals postpartum prior to hospital discharge recruited from a single tertiary …

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Increased dose of H1N1 pandemic influenza vaccine during pregnancy improves immunity in mothers and infants

Dhvanir Kansara, Martina Košíková, Patricia L. Milletich, Jie Zhou et autres

Abstract Maternal-infant immunity against influenza is improved through vaccination during pregnancy. We conducted an in-depth analysis of antibody (Ab) responses in sera from pregnant and non-pregnant women immunized with an unadjuvanted inactivated influenza A (H1N1) monovalent vaccine during the 2009 pandemic ( …

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