Anna Thawanny Gadelha Moura

Influência do sistema imune no sucesso da descontinuação dos inibidores de tirosina quinase na leucemia mieloide crônica

Tarcísio Paulo Almeida Filho, Bárbara Rebeca Alves Pereira, Cinthya Cavalcante de Andrade, Acy Telles de Souza Quixadá et autres

Objetivo: Realizar análise e revisão dos principais artigos disponíveis sobre a influência do sistema imune no sucesso da descontinuação dos inibidores de tirosina quinase na leucemia mieloide crônica. Revisão bibliográfica: O conceito recente de remissão livre de tratamento (RLT) surge como um …

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Papel dos exossomos na leucemia mieloide crônica

Anna Thawanny Gadelha Moura, Pedro Aurio Maia Filho, Tarcísio Paulo de Almeida Filho, Suzzy Maria Carvalho Dantas

Objetivo: Identificar o papel dos exossomos na Leucemia Mieloide Crônica (LMC), destacando sua origem, impacto na progressão da doença, resistência a fármacos e potencial terapêutico. Métodos: Revisão integrativa com artigos entre 2013 e 2025, nos idiomas português, inglês e espanhol, com texto …

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Obliterans With Organizing Pneumonia: A Possible Misdiagnosis of Lung Graft-Versus-Host Disease in Posttransplant Patients With COVID-19

Fernando Barroso Duarte, Romélia Pinheiro Gonçalves Lemes, Karine Sampaio Nunes Barroso, João Paulo Solar Vasconcelos et autres

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CANCER, POVERTY AND LACK OF ACCESS TO THE BEST THERAPIES IN BRAZIL

Fernando Barroso Duarte, Anna Thawanny Gadelha Moura, Romélia Pinheiro Gonçalves Lemes

This year, I followed a young patient who is being investigated for a probable leukemia, He said he was a gardener. I tried to explain what his diagnostic hypothesis was, but I had a distinct feeling that he hadn't quite understood the …

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COMPARATIVE ANALYSIS OF THE DATA ON THE INFLUENCE OF THE SARS-COV-2 PANDEMIC ON BONE MARROW TRANSPLANTATION AND THE PROTOCOLS ADOPTED IN BRAZIL BETWEEN MAY AND JUNE 2020

Fernando Barroso Duarte, Anna Thawanny Gadelha Moura, Abrahão Elias Hallack Neto, Adriana Seber et autres

This is an observational and cross-sectional study, carried out in May 2020, targeting adult individuals of both sexes who are members of multiprofessional teams working in Brazilian HSCT units in the current period of the pandemic by completing and analyzing a questionnaire. …

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Myelodysplastic Syndrome / Secondary Acute Myeloid Leukemia: role of the allogeneic hematopoietic stem cell transplantation

Yhasmine Delles Oliveira Garcia, Juliene Lima Mesquita, Yensy Mariana Zelaya Rosales, Anna Thawanny Gadelha Moura et autres

Secondary Acute Myeloid Leukemia (s-AML) refers to the development of leukemia after cytotoxic therapy, immunosuppressive therapy, radiation or an antecedent hematological disorder, such as Myelodysplastic Syndrome (MDS). A s-AML corresponds to 10% to 30% of AML cases and is defined by the …

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Hemostasis profile in COVID-19 infection

Fernando Barroso Duarte, Rosângela Pinheiro Gonçalves Machado, Romélia Pinheiro Gonçalves Lemes, Isabella Araújo Duarte et autres

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Impact of Treatment Prior to Allogeneic Transplantation of Hematopoietic Stem Cells in Patients with Myelodysplastic Syndrome: Results of the Latin American Bone Marrow Transplant Registry

Fernando Barroso Duarte, Anna Thawanny Gadelha Moura, Vaneuza Araújo Moreira Funke, Virgílio Antônio Rensi Colturato et autres

It has been suggested that bridging therapy with intensive chemotherapy and/or hypomethylating agents followed by hematopoietic stem cell transplantation (HSCT) can be valuable in the treatment of patients with myelodysplastic syndromes (MDS). However, the influence of this approach on HSCT outcomes remains …

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Influence of the Cell Source and Conditioning System on Hematopoietic Stem Cell Transplantation in Myelodysplastic Syndrome.

Fernando Barroso Duarte, Anna Thawanny Gadelha Moura, Vaneuza Araújo Moreira Funke, Virgílio Antônio Rensi Colturato et autres

Introduction Several factors may interfere with the response to hematopoietic stem cell transplantation (HSCT) in myelodysplastic syndrome (MDS). Objective To evaluate the effect of cell source and type of conditioning on HSCT outcome in MDS. Methods We analyzed data from 258 MDS …

Prolonged response to recombinant human erythropoietin treatment in patients with myelodysplastic syndrome at a single referral centre in Brazil

Anna Thawanny Gadelha Moura, Fernando Barroso Duarte, Maritza Cavalcante Barbosa, Romélia Pinheiro Gonçalves Lemes

OBJECTIVES: To evaluate the effects of epoetin (EPO) alfa treatment on overall survival, event-free survival and response duration in patients with myelodysplastic syndrome (MDS) who were treated at a haematological referral centre in northeastern Brazil. METHODS: This was a retrospective cohort study …

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Isochromosome i(7)(q10) in Myelodysplastic Syndrome – Case Report

Yhasmine Delles Oliveira Garcia, Juliene Lima Mesquita, Yensy Mariana Zelaya Rosales, Tallyta Ellen Jesus dos Santos et autres

ackground: Myelodysplastic syndromes (MDS) belong to the group of haematological neoplasms characterised by cellular dysplasia and predisposition to the development of acute myeloid leukaemia.Isochromosome 7 [i(7q)] is a cytogenetic abnormality characterised by an abnormal chromosome, in which the short arm is absent …

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Presence of CD34+ in Megakaryocytes in Association With p53 Expression Predicts Unfavorable Prognosis in Low-risk Myelodysplastic Syndrome Patients

Fernando Barroso Duarte, Talyta Ellen de Jesus dos Santos, Maritza Cavalcante Barbosa, Anna Thawanny Gadelha Moura et autres

BACKGROUND/AIM: Although risk stratification using the Prognostic Scores Systems (IPSS, WPSS and IPSS-R) incorporate key information about prognosis of patients with Myelodysplastic syndromes (MDS), patients classified as low-risk may evolve rapidly and aggressively, despite a "favorable" prognostic stratification. The aim of this …

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