Jiamin Xia

Lifesaving Cooling Effect: Spatially Explicit Scaling Up Urban Green Coverage to Avert Heat-Related Mortality across China

Jiayu Wu, Jiamin Xia, Qingxu Huang, Yue Wang et autres

Heatwaves, intensified by climate change and urban heat islands, pose a severe threat to global public health, particularly in densely populated cities. While the cooling effect of urban green spaces is recognized, quantifying their impact on heatwave-related mortality spatially explicitly at the …

gb, cn, hu, au, by, us, tw (code pays fourni par la source)

Unified and Semantically Grounded Domain Adaptation for Medical Image Segmentation

Xin Wang, Yin Guo, Jiamin Xia, Kaiyu Zhang et autres

Most prior unsupervised domain adaptation approaches for medical image segmentation are narrowly tailored to either the source-accessible setting, where adaptation is guided by source-target alignment, or the source-free setting, which typically resorts to implicit adaptation mechanisms such as pseudo-labeling and network distillation. …

us (code pays fourni par la source)

Voxel-Wise Quantification and Multi-planar Visualization of Plaque Contrast Enhancement in Intracranial Vessel Wall MRI

Yin Biao Guo, Maoxue Wang, Beibei Sun, Dan Cheng et autres

Background: Contrast enhancement (CE) of intracranial atherosclerotic plaques is a valuable biomarker for identifying culprit plaques in ischemic stroke, but current assessment methods are limited by qualitative approaches and artifact susceptibility. Purpose: To develop and validate a semi-automated method for visualization and …

us, cn (code pays fourni par la source)

Unified and Semantically Grounded Domain Adaptation for Medical Image Segmentation

Xin Wang, Yin Biao Guo, Jiamin Xia, Kaiyu Zhang et autres

Most prior unsupervised domain adaptation approaches for medical image segmentation are narrowly tailored to either the source-accessible setting, where adaptation is guided by source-target alignment, or the source-free setting, which typically resorts to implicit adaptation mechanisms such as pseudo-labeling and network distillation. …

Correction: Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage

Min Liu, Yuanyuan Li, Zhilin Deng, Ke Zhang et autres

Figure 5Cc2 and the middle image in the upper row of Figure 6H, Figure 5Hh1 and Figure S15Cc1, the images in these two groups were unintentionally duplicated during figure preparation. These errors occurred due to an oversight when we arranged the individual …

cn, gb (code pays fourni par la source)

Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage

Min Liu, Yuanyuan Li, Zhilin Deng, Ke Zhang et autres

Mutation in genes involved in DNA replication continuously disrupt DNA replication and give rise to genomic instability, a critical driver of oncogenesis. To prevent leukemia, immature T lymphocytes with genomic instability often undergo rapid cell death during development. However, the mechanism by …

cn, gb (code pays fourni par la source)

Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage

Sizhou Huang, Min Liu, Yuanyuan Li, Zhilin Deng et autres

cn, gb (code pays fourni par la source)

MCM5 mutation leads to silence of Stat1-bcl2 and accelerates the apoptosis of immature T lymphocytes with DNA damage

Min Liu, Jiamin Xia, Ke Zhang, Yuanyuan Li et autres

Abstract During T lymphocyte development, immature T lymphocyte undergoes V(D)J rearrangement of T-cell receptor (TCR) genes to further develop to functional T cells. Upon this situation, additional DNA damage coming from the mutation of DNA replication genes sensitively makes immature T cells …

cn, gb (code pays fourni par la source)

Mcm5 Represses Endodermal Migration through Cxcr4a-itgb1b Cascade Instead of Cell Cycle Control

Yu Zhang, Jiamin Xia, Min Liu, Bingyu Chen et autres

Minichromosome maintenance protein 5 (MCM5) is a critical cell cycle regulator; its role in DNA replication is well known, but whether it is involved in the regulation of organogenesis in a cell cycle-independent way, is far from clear. In this study, we …

cn, gb (code pays fourni par la source)

ALKBH5 promotes cadmium-induced transformation of human bronchial epithelial cells by regulating PTEN expression in an m6A-dependent manner

Luyao Li, Mei Ling Zhou, Biyun Chen, Qin Wang et autres

Cadmium is a carcinogenic heavy metal that poses a severe threat to human beings. The underlying mechanism, however, remains elusive. N6-methyladenosine (m6A) is the most abundant post-transcriptional modification in mRNA that regulates RNA metabolism. Emerging evidence shows that m6A is involved in …

cn (code pays fourni par la source)

Procyanidins mediates antineoplastic effects against non-small cell lung cancer via the JAK2/STAT3 pathway

Yue Wu, Chi Liu, Yuxu Niu, Jiamin Xia et autres

BACKGROUND: Lung cancer is a malignant tumor with one of the highest rates of cancer-related morbidity and mortality worldwide. Non-small cell lung cancer (NSCLC) account for 85% of all lung cancers and have a poor prognosis. Proanthocyanidins (PCs) are polyphenolic compounds that …

cn (code pays fourni par la source)

The expression of zebrafish NAD(P)H:quinone oxidoreductase 1(nqo1) in adult organs and embryos

Min Liu, Jinping Guo, Bingyu Chen, Jiamin Xia et autres

cn (code pays fourni par la source)