Mariëlle J. L. Romberg-Camps

Switching standard dosed intravenous to subcutaneous infliximab leads to similar drug exposure in inflammatory bowel disease patients independent of concomitant immunosuppressants (SHUFFLE study)

Lieke M. J. van de Ven ‐ van Dinter, Mariëlle J. L. Romberg-Camps, Dennis R. Wong, Adriaan A. van Bodegraven et autres

AIMS: Subcutaneous (SC) flat-dose infliximab (IFX) biosimilar offers potential advantages over intravenous (IV) weight-based dosing. Prospective pharmacokinetic data and clinical outcomes in inflammatory bowel disease (IBD) are scarce, since drug approval was primarily based on a rheumatoid-arthritis study population concomitantly using methotrexate. …

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Recurrence After Ileocolic Resection for Crohn’s Disease: Further Unraveling the Search for Risk Factors

Alexander R.P.K.M. van Renterghem, Sander M. J. van Kuijk, Eric H J Belgers, Mariëlle J. L. Romberg-Camps et autres

BACKGROUND: Crohn's disease causes chronic intestinal inflammation, often requiring surgery. Postoperative recurrence is common, especially at the anastomosis, with varying recurrence rates. OBJECTIVE: Identifying risk factors for recurrence is crucial for optimizing treatment. This study aims to assess traditional and novel risk …

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Lifestyle and psychosocial factors in inflammatory bowel disease: Prevalence, impact, motivation, and support needs

Karlijn Demers, Evelien M. B. Hendrix, Ashkan Rezazadeh Ardabili, Quirine M. Bredero et autres

BACKGROUND AND AIM: Lifestyle and psychosocial factors impact mucosal inflammation and well-being of Inflammatory Bowel Disease (IBD) patients. However, lifestyle assessment and interventions are not standard care. The aim of this study was to estimate the occurrence of and gather patients' perspectives …

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Preoperative Body Composition Parameters Are Associated With Postoperative Outcomes in Patients With Crohn’s Disease

Michiel T. Bak, Karlijn Demers, Oddeke van Ruler, Marieke J. Pierik et autres

BACKGROUND & AIMS: Preoperative body composition is a potential modifiable risk factor for poor postoperative outcomes in Crohn's disease (CD). This study aimed to investigate the association of preoperative body composition parameters with postoperative complications and endoscopic postoperative recurrence (ePOR) in patients …

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The Risk of Mild, Moderate, and Severe Infections in IBD patients – A prospective, multicentre observational cohort study (PRIQ)

Ashkan Rezazadeh Ardabili, Dirk van Esser, D Wintjens, Mia Cilissen et autres

BACKGROUND: In light of the growing number of treatment options, the benefit-risk balance of IBD drugs is increasingly important in clinical decision-making. Post-marketing surveillance studies are pivotal to assess infection risk, yet mainly focus on severe infections. This study aimed to assess …

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Combined Clinical and Histopathological Risk Stratification for Prediction of (severe) Endoscopic Postoperative Recurrence in Patients with Crohn’s Disease after Ileocolic Resection

Michiel T. Bak, Lindsey Oudijk, Ariadne H.A.G. Ooms, Evelien M. J. Beelen et autres

OBJECTIVE: This study assessed the association of histopathological features in the resection specimen of CD patients with (severe) endoscopic postoperative recurrence (ePOR) in a large prospective, multicenter cohort study. SUMMARY BACKGROUND DATA: The predictive value of histopathologic features of the intestinal resection …

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Mo1855: COMBINED CLINICAL AND HISTOPATHOLOGICAL RISK STRATIFICATION FOR PREDICTION OF (SEVERE) ENDOSCOPIC POSTOPERATIVE RECURRENCE IN PATIENTS WITH CROHN’S DISEASE AFTER ILEOCOLIC RESECTION

Michiel T. Bak, Lindsey Oudijk, Ariadne H.A.G. Ooms, Evelien M. J. Beelen et autres

1198: PREOPERATIVE BODY COMPOSITION PARAMETERS ARE ASSOCIATED WTIH POSTOPERARTIVE COMPLICATIONS AND ENDOSCOPIC POSTOPERATIVE RECURRENCE IN PATIENTS WITH CROHN’S DISEASE

Michiel T. Bak, Karlijn Demers, Oddeke van Ruler, Marie J. Pierik et autres

Mo1253: EFFECT OF NOVEL BIOLOGICALS AND SMALL MOLECULES ON SUBJECTIVE DISEASE CONTROL IN IBD

Arta Aliu, Zlatan Mujagic, Mariëlle J. L. Romberg-Camps, Steven F. G. Jeuring et autres

The Impact of Postoperative Prophylactic Medication on Long‐Term Surgical, Severe Endoscopic and Endoscopic or Radiologic Recurrence Following Primary Ileocecal Resection in Patients With Crohn's Disease

Sebastiaan ten Bokkel Huinink, Michiel T. Bak, Evelien M. J. Beelen, Nicole Stephanie Erler et autres

BACKGROUND: The impact of prophylactic medication following ileocecal resection (ICR) for Crohn's disease (CD) merits further elucidation. Prophylactic medication following ileocecal resection (ICR) is recommended in patients with Crohn's disease (CD), particularly in patients at increased risk of recurrence, but the impact …

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P0396 Combined clinical and histopathological risk stratification for prediction of (severe) endoscopic postoperative recurrence in patients with Crohn’s disease after ileocolic resection

M Bak, Lindsey Oudijk, Ariadne H.A.G. Ooms, Evelien M. J. Beelen et autres

Abstract Background The predictive value of histopathologic features of the intestinal resection specimen for the risk of Crohn’s disease (CD) recurrence after ileocolic (re-)resection (ICR) remains a matter of debate. Therefore, this study assessed the association of histopathological features in the resection …

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P0402 Preoperative body composition parameters are associated with postoperative complications and endoscopic postoperative recurrence in patients with Crohn’s disease

M Bak, K Demers, Oddeke van Ruler, Diederik van Dijk et autres

Abstract Background Alterations in body composition are common among patients with Crohn’s disease (CD) and may represent a modifiable risk factor for dismal postoperative outcomes. This study aimed to investigate the association of preoperative body composition with postoperative complications and endoscopic postoperative …

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