Farheen Farzana

Longitudinal spatial mapping of lipid metabolites reveals pre-symptomatic changes in the hippocampi of Huntington's disease transgenic mice

Farheen Farzana, Malcolm J. McConville, Thibault Renoir, Shanshan Li et autres

In Huntington's disease (HD), a key pathological feature includes the development of inclusion-bodies of fragments of the mutant huntingtin protein in the neurons of the striatum and hippocampus. To examine the molecular changes associated with inclusion-body formation, we applied MALDI-mass spectrometry imaging …

au (code pays fourni par la source)

KineticMSI, an R-based framework for relative quantification of spatial isotopic incorporation in mass spectrometry imaging experiments

Farheen Farzana, Federico Martínez-Seidel, Anthony J. Hannan, Danny M. Hatters et autres

ABSTRACT Kinetic mass spectrometry imaging (kMSI) integrates imaging-MS with stable isotope labelling to elucidate metabolic fluxes in a spatiotemporal manner. kMSI studies are hampered by high volumes of complex data and a lack of computational workflows for data analysis that additionally address …

us, au, de (code pays fourni par la source)

Investigating mechanisms of mutant huntingtin toxicity by spatially mapping lipid metabolites in a mouse model of Huntington’s disease

Farheen Farzana

© 2022 Farheen Farzana

P.044 Effects of exercise and environmental enrichment in serotonin transporter knock-out mice

Jake Rogers, F. Chen, Davor Stanić, Farheen Farzana et autres

au, fr (code pays fourni par la source)

Paradoxical effects of exercise on hippocampal plasticity and cognition in mice with a heterozygous null mutation in the serotonin transporter gene

Jake Rogers, Feng Chen, Davor Stanić, Farheen Farzana et autres

BACKGROUND AND PURPOSE: Exercise is known to improve cognitive function, but the exact synaptic and cellular mechanisms remain unclear. We investigated the potential role of the serotonin (5-HT) transporter (SERT) in mediating these effects. EXPERIMENTAL APPROACH: Hippocampal long-term potentiation (LTP) and neurogenesis …

au, fr (code pays fourni par la source)

The Impact of Inflammation on Brain Function and Behavior in Rodent Models of Affective Disorders

Farheen Farzana, Thibault Renoir, Anthony J. Hannan

au (code pays fourni par la source)

Contributors

Diana Ahmetspahic, Judith Alferink, George Anderson, Katarina Arandjelovic et autres

de, au, dk, gb, us, fr, ca (code pays fourni par la source)

Effects of exercise and environmental enrichment in serotonin transporter (5-HTT) knock-out mice

Jake Rogers, Farheen Farzana, Fei Cheng, S. Li et autres

Can individual home‐based cognitive stimulation therapy benefit Parkinson's patients with mild to moderate cognitive impairment?

Farheen Farzana, Sreekanth Vemula, Mohammed Khaliq Mohiuddin, Vasavi Mohan et autres

in (code pays fourni par la source)

Non-Pharmacological Interventions for Enhancing Brain Plasticity and Promoting Brain Recovery: A Review

Farheen Farzana, Yog Raj Ahuja, Sreekanth Vemula

Despite the incredible advancements made in the field of neuroscience, neurodegenerative disorders arising from the pathological forms of neural plasticity, continue to remain the primary cause of increased death rate. While significant progress has been made in the introduction of novel pharmacological …