Roberta Maria da Silva Oliveira Safranauskas

Semi‐Automated Interphase FISH ( iFISH ) Spot Scoring in CD138 ‐Positive Cells: Validation Study for Genetic Abnormalities Detection in Multiple Myeloma

Daniela Borri, Chin Jia Lin, Victor Camillo, Renata Kiyomi Kishimoto et autres

We conducted a study to validate the automated scoring of Fluorescent in Situ Hybridization (FISH) in a routine cytogenetics laboratory using selected CD138-positive cells in samples from patients with multiple myeloma. A workstation was optimized based on the manufacturer's configurations. Six commercial …

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Asymptomatic T prolymphocytic leukemia: case report and literature review

Luiz Frederico Bezerra Honorato, Elizabeth Xisto Souto, Roberta Maria da Silva Oliveira Safranauskas, Renata Kiyomi Kishimoto et autres

T-cell prolymphocytic leukemia is a rare and aggressive mature T-cell malignancy that usually presents with marked lymphocytosis, hepatosplenomegaly, lymphadenopathy, and B symptoms. However, a minority of patients present with an indolent, asymptomatic form. Case Report: A 44-year-old man was diagnosed with asymptomatic …

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Validação da sonda para o gene SRY para estudo de quimerismo sexual em transplantados de medula óssea, utilizando a metodologia de FISH automatizado

Daniela Borri, Lauren Ingrid Santos Moreira da Conceição, Roberta Maria da Silva Oliveira Safranauskas, Maria Gabriella Cordeiro et autres

Introdução: A determinação do quimerismo sexual pós-transplante de células-tronco hematopoiéticas (TCTH) é fundamental para o monitoramento da enxertia. Ela é realizada por repetições curtas em tandem (STR, short tandem repeats), por cariótipo e por hibridação in situ fluorescente (FISH, fluorescence in situ …

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Cytogenetic findings in testicular relapse of multiple myeloma: case report and literature review

Marília Bazzo Catto, Roberta Maria da Silva Oliveira Safranauskas, Tarcila Santos Datoguia, Renata Kiyomi Kishimoto et autres

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Fluorescence in situ hybridization (FISH) in imprint of biopsies suspected of lymphoproliferative neoplasms: report on 17 cases

Roberta Maria da Silva Oliveira Safranauskas, Denise da Cunha Pasqualin, Renata Kiyomi Kishimoto, Maria Marta Silva et autres

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MYC amplification in leukemia detected by cytogenetics

Roberta Maria da Silva Oliveira Safranauskas, Maria Gabriella Cordeiro, Elvira Deolinda Rodrigues Pereira Velloso

Cytogenetic studies of three patients aged between 65 and 76 years with newly de novo acute myeloid leukemia, AML, NOS according to WHO classification (one case AML without maturation, one case acute myelomonocytic leukemia and one case AML with maturation). G-band karyotyping …

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Cytogenetic studies for cMYC, BCL2 and BCL6 genes in neoplasm: comparison of karyotype, FISH in paraffin-embedded tissue and FISH in methanol-acetic acid-fixed cells suspensions

Caroline Henriques Garcia, Roberta Maria da Silva Oliveira Safranauskas, Alanna Mara Pinheiro Sobreira Bezerra, Elvira Deolinda Rodrigues Pereira Velloso

hematol transfus cell ther. ( 2 0 2 1 );4 3(4):521-526 w w w . h t c t . c o m . b r Hematology, Transfusion and Cell Therapy Letter to the Editor Cytogenetic studies for cMYC, BCL2 and BCL6 …

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Detection of cytogenetic abnormalities in mature B-cell neoplasms: the value of cultures with different mitogens

Roberta Maria da Silva Oliveira Safranauskas, Elvira Deolinda Rodrigues Pereira Velloso

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