Roman Sokol

Glycoprofiling of proteins as prostate cancer biomarkers: A multinational population study

Andrea Pinkeová, Adela Tomikova, Anikó Bertóková, Eva Fabinyova et autres

The glycoprofiling of two proteins, the free form of the prostate-specific antigen (fPSA) and zinc-α-2-glycoprotein (ZA2G), was assessed to determine their suitability as prostate cancer (PCa) biomarkers. The glycoprofiling of proteins was performed by analysing changes in the glycan composition on fPSA …

de, cz, at, sk (code pays fourni par la source)

Increasing the accuracy of prostate cancer diagnostics by glycoprofiling of selected serum oncomarkers: clinical and economic impact per patient

Tomáš Bertók, Roman Sokol, Juraj Fillo, Jan Tkáč

V práci stručne opisujeme možnosti využitia metód tzv. tekutej biopsie, teda detekcie vysoko nádorovo-špecifických markerov z telových tekutín, na diagnostiku karcinómu prostaty (CaP). V tomto prípade je dôležité hodnotiť biomarkery, ktoré sú orgánovo-špecifické, ako napríklad kalikreíny (rôzne formy PSA), avšak tie nie …

es, sk (code pays fourni par la source)

Glycoprofiling of proteins as prostate cancer biomarkers: a multinational population study

Andrea Pinkeová, Adela Tomikova, Anikó Bertóková, Eva Fabinyova et autres

Abstract The glycoprofiling of two proteins, the free form of the prostate-specific antigen (fPSA) and zinc-α-2-glycoprotein (ZA2G), was assessed to determine their suitability as prostate cancer (PCa) biomarkers. The glycoprofiling of proteins was performed by analysing changes in the glycan composition on …

sk, de, cz, at (code pays fourni par la source)

Efficacy and Safety of Autologous Dendritic Cell–Based Immunotherapy, Docetaxel, and Prednisone vs Placebo in Patients With Metastatic Castration-Resistant Prostate Cancer

Nicholas J. Vogelzang, Tomasz M. Beer, Winald R. Gerritsen, Stéphane Oudard et autres

IMPORTANCE: DCVAC/PCa is an active cellular immunotherapy designed to initiate an immune response against prostate cancer. OBJECTIVE: To evaluate the efficacy and safety of DCVAC/PCa plus chemotherapy followed by DCVAC/PCa maintenance treatment in patients with metastatic castration-resistant prostate cancer (mCRPC). DESIGN, SETTING, …

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Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Prostate Cancer: The Primary Results of the PRONOUNCE Randomized Trial

Renato D. Lópes, Celestia S. Higano, Susan F. Slovin, Adam J. Nelson et autres

Background: The relative cardiovascular safety of gonadotropin-releasing hormone (GnRH) antagonists compared with GnRH agonists in men with prostate cancer and known atherosclerotic cardiovascular disease remains controversial. Methods: In this international, multicenter, prospective, randomized, open-label trial, men with prostate cancer and concomitant atherosclerotic …

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Analysis of serum glycome by lectin microarrays for prostate cancer patients - a search for aberrant glycoforms

Tomáš Bertók, Eduard Jáné, Nikola Chrenekova, Štefánia Hrončeková et autres

sk, qa, ch (code pays fourni par la source)

Advanced impedimetric biosensor configuration and assay protocol for glycoprofiling of a prostate oncomarker using Au nanoshells with a magnetic core

Tomáš Bertók, Lenka Lorencová, Štefánia Hrončeková, Veronika Gajdošová et autres

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Synthesis and characterization of Au nanoshells with a magnetic core and betaine derivatives

Tomáš Bertók, Lenka Lorencová, Štefánia Hrončeková, Veronika Gajdošová et autres

The article describes preparation, characterization and further modification of hybrid magnetic particles (Au nanoshells with a magnetic core (MPs@silica@Au)) by zwitterionic molecules bearing diazonium functional groups. Such hybrid magnetic particles modified by zwitterionic molecules exhibit the following features: •Responsiveness towards external magnetic …

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Aberrant sialylation of a prostate-specific antigen: Electrochemical label-free glycoprofiling in prostate cancer serum samples

Dominika Pihíková, Peter Kasák, Petra Kubanikova, Roman Sokol et autres

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Development of Lectin-Based Biosensor for Glycoprofiling of Clinical Samples: Focus on Prostate Cancer

Dominika Pihíková, Štefan Belický, Tomáš Bertók, Roman Sokol et autres