Lisa Gagalis

Effect of IL-4RαR576 polymorphism on response to dupilumab in asthma, a genotype-stratified, randomized, placebo- controlled trial (IDEA Trial): Design, Rationale, Methods, Strategies, and Lessons Learned

Wanda Phipatanakul, Elliot Israel, David T. Mauger, Susan J. Kunselman et autres

BACKGROUND: Asthma is a heterogeneous chronic disease, disproportionately affecting racial and ethnic minorities, with persistence and severity influenced by both environmental and genetic factors. The IL-4RαR576 variant occurs more commonly in racially minoritized, and the genotype, independent of race, is associated with …

us (code pays fourni par la source)

Relationships between lung function, allergy, and wheezing in urban children

A Konno, Vinay Goswamy, Agustin Calatroni, Peter J. Gergen et autres

us (code pays fourni par la source)

Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial

Daniel J. Jackson, Leonard B. Bacharier, Peter J. Gergen, Lisa Gagalis et autres

us (code pays fourni par la source)

Childhood Asthma Incidence, Early and Persistent Wheeze, and Neighborhood Socioeconomic Factors in the ECHO/CREW Consortium

Antonella Zanobetti, Patrick Ryan, Brent A. Coull, Cole Brokamp et autres

Importance: In the United States, Black and Hispanic children have higher rates of asthma and asthma-related morbidity compared with White children and disproportionately reside in communities with economic deprivation. Objective: To determine the extent to which neighborhood-level socioeconomic indicators explain racial and …

us (code pays fourni par la source)

Phenotype-directed Therapy with Mepolizumab for Urban Children with Exacerbation-Prone Asthma

Daniel J. Jackson, Leonard B. Bacharier, Peter J. Gergen, Lisa Gagalis et autres

us (code pays fourni par la source)

Expression quantitative trait locus fine mapping of the 17q12–21 asthma locus in African American children: a genetic association and gene expression study

Carole Ober, Chris McKennan, Kevin M. Magnaye, Matthew C. Altman et autres

us (code pays fourni par la source)