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Profil bibliographique

Liyuan Xiang

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

64Publications signalées
1177Citations signalées
2Affiliations récentes

Les institutions déclarées

Les domaines associés

Gut microbiota and healthInflammatory Bowel DiseaseKidney Stones and Urolithiasis TreatmentsPelvic floor disorders treatmentsUrinary Tract Infections Management

Les publications récentes

Accès ouvert 2026 article OpenAlex

Clusterin elaborated by renal tubular epithelial cells under high oxalate stress serves as a matrix protein to facilitate kidney stone formation

Yucheng Ma, Linhu Liu, Zhongyu Jian, Lede Lin et autres

Calcium oxalate (CaOx) kidney stone is prevalent while the molecular mechanisms are not yet fully understood. The organic matrix of stones is rich in protein and has been considered to play a important role in stone aggregation and growth. Through multi-omics approaches, …

cn (code pays fourni par la source)

0 citations Cellular and Molecular Life Sciences
Accès ouvert 2025 preprint OpenAlex

3-Phenylpropionic acid, a microbiota-derived polyphenol metabolite linked to hippuric acid, ameliorates colitis as a colon-enriched PPAR-γ agonist

Liyuan Xiang, Wanrong Luo, Wenjie Zhang, Wenhua Lai et autres

Abstract Polyphenols are promising therapeutics for Crohn’s disease (CD), yet their bioavailability is largely dependent on the gut microbiome. The bioactive metabolites, metabolic pathways, and anti-inflammatory mechanisms underlying their effects remain poorly defined. We identified hippuric acid (HIPA) as a biomarker of …

cn, sa (code pays fourni par la source)

0 citations bioRxiv (Cold Spring Harbor Laboratory)
Accès ouvert 2025 article OpenAlex

Gut microbiota-bile acid crosstalk contributes to calcium oxalate nephropathy through Hsp90α-mediated ferroptosis

Linhu Liu, Yucheng Ma, Zhongyu Jian, Banghua Liao et autres

The gut microbiota and its metabolites have been implicated in calcium oxalate (CaOx) nephrolithiasis, while the precise mechanism remains unclear. We report that the gut microbiota dysbiosis in patients with CaOx nephrolithiasis results in an elevated level of deoxycholic acid (DCA) and …

cn (code pays fourni par la source)

12 citations Cell Reports
Accès ouvert 2025 article OpenAlex

Single-Cell RNA Sequencing Analysis Reveals the Role of Macrophage-Mediated CD44–AKT–CCL2 Pathways in Renal Tubule Injury during Calcium Oxalate Crystal Formation

Xi Jin, Zhongyu Jian, Yucheng Ma, Jun Wen et autres

Oxalate-induced crystalline kidney injury is a common form of crystal nephropathy. The accumulation of calcium oxalate (CaOx) crystal could lead to renal epithelium injury and inflammation. The underlying cellular events in kidney after CaOx crystal formation are largely unknown. This study was …

cn (code pays fourni par la source)

12 citations Research

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