Olawale F. Ayilara

A protocol paper for a pilot randomized controlled trial assessing the feasibility and acceptability of group medical visits for anxiety and depression in adults

Christian Kordan, Jennifer Hensel, Jitender Sareen, Jane Moody et autres

BACKGROUND: Group medical visits (GMVs) offer a promising approach to address mental health challenges, particularly in settings with limited access to psychiatric care. Although GMVs have been studied in chronic disease management, their application in mental health, especially through randomized controlled trials …

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Sensitivity of the Patient-Health Questionnaire (PHQ-9) items to change in three clinical trials in low- and middle-income countries

Olawale F. Ayilara, A. W. White, Gerard Dunleavy, Mark Anthony Ferro et autres

BACKGROUND: The 9-item Patient Health Questionnaire (PHQ-9) is a valid and widely used self-reported tool for assessing depressive symptoms. Although previous studies have demonstrated its sensitivity to change at the summary score level, there is limited investigation of the sensitivity of individual …

ca, gb, au (code pays fourni par la source)

Therapeutic-dose heparin combined with antiplatelets in noncritically ill patients with COVID-19: a secondary analysis of a multiplatform randomized controlled trial

Sylvain Lother, Wen Teng, Olawale F. Ayilara, Brett L. Houston et autres

Background: Therapeutic-dose heparin improves outcomes in noncritically ill patients hospitalized for COVID-19. The effect of antiplatelet exposure in addition to therapeutic-dose heparin is unknown. Objectives: To evaluate the effect of antiplatelet exposure in addition to therapeutic-dose heparin on survival without organ support. …

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Comparison of Prophylactic and Therapeutic Platelet Transfusion Strategies in Manitoba: A Retrospective Cohort Study

Andrea A. Pérez Soriano, Brett L. Houston, Neelan Sriranjan, Emily K. Rimmer et autres

Background:Autologous bone marrow transplantation (BMT) is associated with severe thrombocytopenia, yet optimal use of platelet transfusions is unclear. Subgroup analyses from prior trials1,2 demonstrated no difference in major bleeding among patients treated with prophylactic (to prevent bleeding) or therapeutic (to treat bleeding) …

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Comparing Methods for Missing Paternal Linkages in Administrative Data

Amani F. Hamad, Barret A. Monchka, Oleguer Plana‐Ripoll, Olawale F. Ayilara et autres

ObjectiveAdministrative data often lacks complete family linkages, particularly to fathers, hindering familial health research. We compared methods to address missing paternal linkages in research investigating the familial transfer of mental disorders. ApproachA population-based cohort study of Manitoba (Canada) born adults, +18 years …

Validating the Ontario Child Health Study Emotional Behavioural Scales‐Brief Version (OCHS‐EBS‐B) in children with chronic physical illness

Mark Anthony Ferro, Olayinka I. Arimoro, Olawale F. Ayilara, Gurkiran K. Dhuga et autres

Abstract Background A substantial proportion of children have a physical illness; these children commonly experience physical–mental comorbidity. To assess child mental health, brief scales that can be used in clinical and research settings are needed. This study assessed the validity and reliability …

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Response shift in coronary artery disease

Oluwaseyi A. Lawal, Olu Awosoga, Maria Santana, Olawale F. Ayilara et autres

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Generating synthetic data from administrative health records for drug safety and effectiveness studies

Olawale F. Ayilara, Robert William Platt, Matt Dahl, Janie Coulombe et autres

Introduction: Administrative health records (AHRs) are used to conduct population-based post-market drug safety and comparative effectiveness studies to inform healthcare decision making. However, the cost of data extraction, and the challenges associated with privacy and securing approvals can make it challenging for …

ca, se, au (code pays fourni par la source)

Response shift in parent-reported psychopathology in children with chronic physical illness

Tolulope T. Sajobi, Olawale F. Ayilara, Gurkiran K. Dhuga, Mark Anthony Ferro

ca, au (code pays fourni par la source)

Estimating Disease Heritability from Electronic Healthcare Records: A Proof-of-Concept Study.

Lisa Marie Lix, Amani F. Hamad, Lin Yan, Joseph A. Delaney et autres

ObjectiveA family history of a chronic disease often predicts disease risk, with predictive value determined by heritability, the proportion of variation in risk explained by inherited genetic factors. Our objective was to assess the validity of disease heritability estimates from electronic healthcare …

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A Synthesis of Algorithms for Multi-Jurisdiction Research in Canada.

Lisa Marie Lix, Viktoriya Vasylkiv, Olawale F. Ayilara, Lindsey J. Dahl et autres

ObjectivesValidation of algorithms to identify health conditions (e.g., diabetes) or service use (e.g., high-cost users) in administrative data is time-consuming and expensive. Many algorithms are only assessed in a single jurisdiction, which may limit generalizability. Our study described the characteristics of multi-jurisdiction …

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Estimating longitudinal change in latent variable means: a comparison of non-negative matrix factorization and other item non-response methods

Olawale F. Ayilara, Tolulope T. Sajobi, Ruth Barclay, Mohammad Jafari Jozani et autres

Estimates of longitudinal change in the parameters of latent (i.e. unobserved) variables, including means, are affected by non-response on the items or indicators of the latent variable. This study used Monte Carlo simulation and a numeric example to compare four ordinal item …

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