Amgad N. Makaryus

Primary Brain Malignancies in Interventional Cardiologists: A Literature Review and Hypothesis Formulation to Enhance Awareness and Prospective Studies

Angelo Materia, Iraj Azfal, Samatha Kasturiarachchi, Gustavo Saladin Miller et autres

Abstract Over the past decade there have been numerous reports of primary brain malignancies in physicians utilizing radiation for procedures. Among the highest affected group of physicians are interventional cardiologists (ICs) who routinely require the aid of radiation when performing procedures. Despite …

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Deep Learning Applied to 12-Lead ECGs for Detection of Structural, Metabolic and Systemic Disease

Shlomo Shaulian, Roman Zeltser, Amgad N. Makaryus

The 12-lead electrocardiogram (ECG) is inexpensive, noninvasive, and widely available, but conventional interpretation may not capture subtle signals related to cardiac structure, systemic physiology, and future risk. This review examines the use of deep learning-enabled ECG analysis beyond conventional arrhythmia detection and …

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Outcomes of Transfer Destination in Patients With STEMI

Ian C. Gilchrist, April E.P. Read, Amgad N. Makaryus, Ellen Kelly et autres

BACKGROUND: The optimal transfer destination for patients with ST-segment elevation myocardial infarction presenting to nonpercutaneous coronary intervention (PCI)-capable hospitals remains unclear, particularly where both enhanced community (EC) hospitals with PCI capability and quaternary centers are available. PROJECT RATIONALE: Guidelines emphasize timely reperfusion …

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Cardiac Myosin-Binding Protein C in Cardiovascular Disease

Chinonso Asuzu, John Catanzaro, Tzvi Fishkin, Amgad N. Makaryus et autres

Cardiac myosin-binding protein C (cMyBPC) is an important sarcomeric regulatory protein that plays a key role in myocardial contraction and relaxation. Through its interactions with thick and thin filament proteins, cMyBPC helps regulate cross-bridge cycling and contributes significantly to overall cardiac performance. …

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Pediatric Hyperlipidemia Guidelines

Nhi D. Nguyen, Tzvi Fishkin, Amgad N. Makaryus, William H. Frishman et autres

Atherosclerotic cardiovascular disease originates in childhood, and cumulative exposure to low-density lipoprotein cholesterol (LDL-C) is a major determinant of lifetime cardiovascular risk. Multiple professional societies have published guidelines for lipid screening, diagnosis, and management in pediatric populations; yet important differences exist among …

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Pompe Disease

Abdullah Ali, Dinushan Thirumavalavan, John N. Catanzaro, Tzvi Fishkin et autres

Pompe disease (glycogen storage disease type 2, acid maltase deficiency) is an uncommon, progressive, autosomal recessive lysosomal storage disorder caused by a lack of the enzyme acid α-glucosidase. The enzyme deficiency results in the abnormal buildup of glycogen in lysosomes, especially in …

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Weight Management Before Pregnancy to Reduce Cardiovascular Risk

Antra Patel, Tzvi Fishkin, Amgad N. Makaryus, William H. Frishman et autres

Cardiovascular disease remains the leading cause of morbidity and mortality among women globally, with growing evidence suggesting that cardiovascular risk can begin developing well before pregnancy, even during the preconception period. Among the most significant contributing factors is excess prepregnancy weight, which …

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When cardiometabolic risk meets myocardial vulnerability in the female heart

Jennifer H. Mieres, Kumar Sarkar, Amgad N. Makaryus

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From Principle to Practice

Jennifer H. Mieres, Natalie M. Cordero, Amgad N. Makaryus, Peter Silver et autres

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Leadless and extracardiac cardiac rhythm management systems: the next generation of pacing and defibrillation

Dhir Gala, Eugene Kim, Amgad N. Makaryus

INTRODUCTION: The complications associated with the use of transvenous leads and device pockets have been a major drawback in the use of traditional cardiac implantable electronic devices. Infections, venous obstruction, and problems in device extraction have been some of the issues. Leadless …

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Multimodality Echocardiographic Assessment of Mitral Regurgitation: An Integrative Approach

James Kim, Ji-Cheng Jason Hsieh, Tanzim Bhuiya, Amgad N. Makaryus

Abstract Mitral regurgitation affects 2% of the world population. Given its potential for severe clinical consequences, reliable assessment is essential for guiding treatment. While advancements in echocardiographic imaging have expanded available diagnostic techniques, no single method has become the gold standard. Current …

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Titre indisponible

Tanzim Bhuiya, Jonathan Sussman, Francis O'Neill, Tashina Dussie et autres

Loneliness has been identified as an important psychosocial factor associated with cardiovascular disease, but the relationship has been underexplored using validated measures. This cross-sectional study analyzed 92 patients from 2018 to 2019 using the Revised UCLA Loneliness Scale to evaluate associations between …

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