Luye Zhang

CRLS1 influences liver metastasis in colon cancer by regulating lipid metabolism pathways

Junbo Mu, Donghao Li, Mengyuan Cao, Luye Zhang et autres

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Integrated transcriptomic analysis and machine learning for characterizing diagnostic biomarkers and immune cell infiltration in fetal growth restriction

Xing Wei, Luyao Cai, Dayuan Shi, Qianqian Sun et autres

Background: Fetal growth restriction (FGR) occurs in 10% of pregnancies worldwide. Placenta dysfunction, as one of the most common causes of FGR, is associated with various poor perinatal outcomes. The main objectives of this study were to screen potential diagnostic biomarkers for …

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Prenatal Diagnosed Agenesis of the Corpus Callosum: Identifying the Underlying Genetic Etiologies

Xing Wei, Luyao Cai, Luye Zhang, Jianping Chen et autres

OBJECTIVE: To assess the genetic etiologies underlying agenesis of the corpus callosum (ACC) and its pregnancy outcomes in the era of next-generation sequencing. METHODS: A retrospective analysis was conducted on prospectively collected prenatal ACC cases in which amniocentesis was performed between January …

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Continental subduction-triggered carbonate metasomatism of the lithospheric mantle: Implications for the deep carbon cycle

Yang Gao, Keqing Zong, Junfeng Zhang, Luye Zhang et autres

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Perinatal outcome and timing of selective fetal reduction in dichorionic diamniotic twin pregnancies: a single-center retrospective study

Gang Zou, Qingfang Ji, Jianping Chen, Luye Zhang et autres

Objective The study aimed to evaluate the pregnancy outcomes of dichorionic diamniotic twin pregnancies that were reduced to singletons at different gestational ages. Study design This was a retrospective cohort study of twin pregnancies that underwent fetal reduction to singletons in a …

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Continental subduction-triggered carbonate metasomatism of the lithospheric mantle: Implications for the deep carbon cycle

Yang Gao, Keqing Zong, Junfeng Zhang, Luye Zhang et autres

Table 1. Mineral assemblage of the Qixia xenoliths in this study.Table 2. In situ Sr isotopic compositions of clinopyroxene in Qixia xenoliths measured by LA-MC-ICP-MS.Table S1-S5 lists the major (wt%) and trace (µg/g) element compositions in USGS reference glasses and minerals (including …

Placental DNA methylation analysis of selective fetal growth restriction in monochorionic twins reveals aberrant methylated CYP11A1 gene for fetal growth restriction

Dayuan Shi, Xinyao Zhou, Luyao Cai, Xing Wei et autres

Fetal growth restriction (FGR) is associated with increased susceptibility to perinatal morbidity and mortality. Evidence suggests that epigenetic changes play critical roles in the regulation of fetal growth. We sought to present a comprehensive analysis of the associations between placental DNA methylation …

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Continental subduction-induced carbonate metasomatism of the lithospheric mantle: Evidence from the Cenozoic mantle xenoliths in the Qixia basalts, North China Craton

Yang Gao, Keqing Zong, Junfeng Zhang, Luye Zhang et autres

Table S1-4S lists the major (wt%) and trace (µg/g) element compositions in minerals (including olivine, clinopyroxene, orthopyroxene, and spinel) from Qixia mantle xenoliths in this study. The major and trace elements of minerals were analyzed in situ by laser ablation inductively coupled …

Synthesis and antitumor activity evaluation in vitro of 4-aminoquinazoline derivatives containing 1,3,4-thiadiazole

Xiaojie Si, Honglin Dai, Chao Gao, Hao Wang et autres

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Synthesis and Antitumor Activity Evaluation in Vitro of 4-aminoquinazoline Derivatives Containing 1,3,4-thiadiazole

Xiaojie Si, Honglin Dai, Chao Gao, Hao Wang et autres

Abstract In order to search for new antitumor drugs with high efficiency and low toxicity, a series of novel 4-aminoquinazoline derivatives containing 1,3,4-thiadiazole group were designed, synthesized and evaluated for antiproliferative activity against four human cancer cell lines (H1975, PC-3, MCF-7 and …

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Synthesis and Antitumor Activity of 2,4,6-Trisubstituted Novel Quinazoline Derivatives Containing Trifluoromethyl

Zhengjie Wang, Honglin Dai, Xiaojie Si, Chao Gao et autres

Carbonate metasomatism of the lithospheric mantle induced by continental subduction in the eastern North China Craton

Yang Gao, Keqing Zong, Luye Zhang