T. A. Raevskaya

Surface Energy Properties of Polylactic Acid Treated with a Gamma Radiation Dose Used for Sterilization

Svetlana A. Bogdanova, А. Р. Гатауллин, Ilgiza F. Shaimukhametova, Dilyara R. Khisamieva et autres

Abstract The effect of γ-irradiation on polylactic acid samples obtained by injection molding has been studied depending on the dose in the range of 10−100 kGy. Determination of the surface energy characteristics of polylactic acid (surface free energy and its components, as …

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EPR Spectra and Antioxidant Activity of Gamma-Irradiated Papain

Sergey V. Tokarev, Irina I. Faingold, Darya A. Poletaeva, A. V. Smolina et autres

The structure and number of paramagnetic centers (PC) trapped in papain γ-irradiated with a dose of 50 to 2300 kGy have been studied using EPR spectroscopy. The radiation-chemical yield G ≈ 6 PC/100 eV during radiolysis at 77 K is six times …

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Effect of Gamma Irradiation Dose on Papain Toxicity

Uguljan Yu. Allayarova, Sergei V. Demidov, S. V. Blokhina, T. A. Raevskaya et autres

Abstract The effect of a wide range of γ-radiation dose from 250 to 3000 kGy on the acute toxicity of papain administered to laboratory animals has been studied. It has been discovered that preliminary γ-irradiation of papain up to 1000 kGy reduces …

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Nrf2-Regulated Antioxidant System in Cells of In Vivo Drug-Resistant P388 Murine Leukemia Strains

А. А. Балакина, T. A. Raevskaya, Vera I. Amozova

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Redox-Active Compounds in the Therapy of Drug-Resistant Murine Leukemia P388 Strains

T. A. Raevskaya, Yu. V. Soldatova, С. А. Гончарова, Irina I. Faingold

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Redox-active compounds in the therapy of drug-resistant murine leukemia P388 strains

T. A. Raevskaya, U. V. Soldatova, С. А. Гончарова, Irina I. Faingold

Nrf2-regulated antioxidant system in cells of in vivo drug-resistant P388 murine leukemia strains

А. А. Балакина, T. A. Raevskaya, Vera I. Amozova

The Increase of Antileukemic Efficiency of Doxorubicin and Other Cytostatics Combined with Platinum(IV)-Nitroxyl Complex ВС118

С. А. Гончарова, T. A. Raevskaya, Elena N. Klimanova, Vasily D. Sen'

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The increase of antileukemic efficiency of doxorubicin and other cytostatics combined with platinum(IV)-nitroxyl complex ВС118

С. А. Гончарова, T. A. Raevskaya, Elena N. Klimanova, Vasily D. Sen'

Nrf2-Dependent Expression of Glutathione Antioxidant System Genes and Redox Status in Cells of In Vivo Drug-Resistant Murine P388 Leukemia Strains

А. А. Балакина, T. A. Raevskaya, Vladimir S. Pavlov, V. A. Mumyatova et autres

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Activity of Antioxidant Enzymes and Content of Reduced Glutathione in Cells of Drug-Resistant Murine Leukemia P388 Strains

А. А. Балакина, T. A. Raevskaya, Vladimir S. Pavlov, V. A. Mumyatova et autres

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Anticancer Activity of Spirocyclic Hydroxamic Acids (Derivatives of 1-Hydroxy-1,4,8-Triazaspiro[4,5]Decan-2-One), Histone Deacetylase Inhibitors

Natalia Akentieva, A. R. Gizatullin, С. А. Гончарова, T. A. Raevskaya et autres

Abstract The effect of 10 racemic spirocyclic hydroxamic acids (CHA 1–10, derivatives of 1-hydroxy-1,4,8-triazaspiro[4,5]decan-2-one), containing pharmacophore imidazolidinone and piperidine fragments with different substituents, on the activity of enzyme histone deacetylase (HDAC) was studied. It was shown that CHA (1–10) inhibit HDAC activity …

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