Accès ouvert
2018
preprint
OpenAlex
Tzung‐Chien Hsieh, Martin A. Mensah, Jean Tori Pantel, Peter Michael Krawitz et autres
Abstract Phenotype information is crucial for the interpretation of genomic variants. So far it has only been accessible for bioinformatics workflows after encoding into clinical terms by expert dysmorphologists. Here, we introduce an approach, driven by artificial intelligence that uses portrait photographs …
de, si, mx, dk, no, it, us, be, gb, at, in, bg, ru, es, il, fr, pl
(code pays fourni par la source)
Accès ouvert
2010
article
OpenAlex
Hilda David-Eden, Alexander S. Mankin, Yael Mandel‐Gutfreund
The ribosome represents a major target for antibacterial drugs. Being a complex molecular machine, it offers many potential sites for functional interference. The high-resolution structures of ribosome in complex with various antibiotics provide a unique data set for understanding the universal features …
il, us, cz
(code pays fourni par la source)
Accès ouvert
2009
article
OpenAlex
Martin Akerman, Hilda David-Eden, Ron Y. Pinter, Yael Mandel‐Gutfreund
Alternative splicing is regulated by splicing factors that serve as positive or negative effectors, interacting with regulatory elements along exons and introns. Here we present a novel computational method for genome-wide mapping of splicing factor binding sites that considers both the genomic …
il
(code pays fourni par la source)
Accès ouvert
2008
article
OpenAlex
Hilda David-Eden, Yael Mandel‐Gutfreund
The ribosome is a complex molecular machine that offers many potential sites for functional interference, therefore representing a major target for antibacterial drugs. The growing number of high-resolution structures of ribosomes from different organisms, in free form and in complex with various …
il
(code pays fourni par la source)