Zhongyuan Lu

Association Between Gut Microbiota Dysbiosis and Bilirubin Metabolism Dysregulation in Children with Heart Failure

Wei Wei, Lisi Zhou, Yuan Huang, Zhongyuan Lu et autres

cn (code pays fourni par la source)

Comparative machine learning modeling of resting energy expenditure estimation in mechanically ventilated children after cardiac surgery

Chenyu Li, Zhiyuan Zhu, Shilin Wang, C Li et autres

cn (code pays fourni par la source)

Causal effects of psoriasis on breast cancer risk: The contribution of emotional distress explored by Mendelian randomization

Lu Ye, Hui Yang, Danyan Qian, Zhongyuan Lu

Psoriasis is a chronic inflammatory disease associated with an increased risk of various cancers, including breast cancer. However, the mechanisms underlying this association remain poorly understood. Negative emotional states, commonly experienced by individuals with psoriasis, may play a role in mediating this …

cn (code pays fourni par la source)

VSMC phenotypic switching in thoracic aortic aneurysm at single‐cell resolution: Trajectories, regulatory circuits, and spatial niches

Zehua Shao, Chunguang Guo, Zhongyuan Lu, Jianyang Liu et autres

Abstract Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disorder characterized by progressive aortic dilation that often culminates in dissection or rupture, with few effective pharmacological interventions currently available. Vascular smooth muscle cells (VSMCs)‐the predominant cellular component of the aortic media‐undergo extensive …

cn (code pays fourni par la source)

Celiac disease increases the risk of pulmonary arterial hypertension: A multivariable Mendelian randomization and mediation analysis

Meng‐Che Wu, Weidong Song, Xin Guo, Zhongyuan Lu et autres

Celiac disease (CeD) has been implicated in several autoimmune and vascular disorders, but its causal role in pulmonary arterial hypertension (PAH) remains uncertain. Summary-level genome-wide association study data for all traits were obtained from the FinnGen consortium and the genome-wide association study …

cn (code pays fourni par la source)

Early, Low-Dose Pulmonary Surfactant Administration in Infants with Post-Cardiotomy Acute Respiratory Distress Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

R. J. ZHANG, Xu Wang, Shoujun Li, Keming Yang et autres

cn (code pays fourni par la source)

RAPID-CHD pathway improves clinical outcomes in neonates with congenital heart disease

Chang Li, Zhongyuan Lu, Shilin Wang, Xiaodong Li et autres

BACKGROUND: Timely and effective management is crucial for neonates with critical congenital heart disease (CCHD). This study investigated the impact of the RAPID-CHD Pathway, a coordinated referral and transport system, compared with conventional management models. METHODS: This retrospective study included neonates (≤ …

cn (code pays fourni par la source)

The clinical outcomes of acute kidney injury substages based on serum cystatin C in pediatric patients undergoing cardiac surgery

Yinan Li, Dongyun Bie, Chao Xiong, Sheng Shi et autres

BACKGROUND: Multiple biomarkers have been identified by previous studies to diagnose acute kidney injury (AKI). The combination of biomarkers with conventional criteria to define AKI substages in order to identify high-risk patients and improve diagnostic accuracy was recommended. Our study aimed to …

cn (code pays fourni par la source)

The effects of standardized intravenous treprostinil in pulmonary arterial hypertension patients after total cavo-pulmonary connection procedure

Xiaofeng Wang, Shilin Wang, Ruihuan Shen, Zhongyuan Lu et autres

OBJECTIVE: Total cavo-pulmonary connection (TCPC) is a palliative treatment for single ventricular malformations. For high-risk patients (preoperative mean pulmonary arterial pressure, mPAP > 15 mmHg), between the inhaled and oral targeted medications, the application of intravenous treprostinil as a bridge therapy to …

cn (code pays fourni par la source)

The effects of standardized intravenous Treprostinil in pulmonary arterial hypertension patients after total cavo-pulmonary connection procedure

Xiaofeng Wang, Shilin Wang, Ruihuan Shen, Zhongyuan Lu et autres

Abstract Objective Total cavo-pulmonary connection (TCPC) is a palliative treatment for single ventricular malformations. For high-risk patients (preoperative mean pulmonary arterial pressure, mPAP > 15 mmHg), between the inhaled and oral targeted medications, the application of intravenous Treprostinil as a bridge therapy …

cn (code pays fourni par la source)

The clinical outcomes of acute kidney injury substages based on serum cystatin C in pediatric patients undergoing cardiac surgery

Yinan Li, Dongyun Bie, Chao Xiong, Sheng Shi et autres

Abstract Background Multiple biomarkers have been identified by previous studies to diagnose acute kidney injury (AKI). Moreover, combination of biomarkers with conventional criteria to define AKI substages so that we can identify high-risk patients and improve diagnostic accuracy were recommended. Our study …

cn (code pays fourni par la source)

The effects of Treprostinil in high-risk patients after total cavo-pulmonary connection procedure

Xiaofeng Wang, Shilin Wang, Zhongyuan Lu, Wenlong Wang et autres

Abstract Background: We hypothesized that administration of Treprostinil after high-risk total cavo-pulmonary connection (TCPC) procedure may be benefit for hemodynamics and post-operative recovery. Methods: From 2015 to 2022, among patients who underwent TCPC procedure and received Treprostinil therapy in our single center, …

cn (code pays fourni par la source)