Diana Campos

Digging into Understudied Sediments: What Lumbriculus variegatus Reveals about Fluoxetine Exposure from the Cellular to the Individual Level

Jacqueline Hilgendorf, Vânia Calisto, Diana Campos, Diogo N. Cardoso et autres

Abstract Sediments accumulate persistent and toxic compounds, yet assessing their effects on benthic species remains challenging. Especially antidepressants, such as fluoxetine, are of concern due to their sediment affinity and potential to disrupt neuroendocrine functions at low concentrations. This study investigated the …

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Toxicity assessment of organic UV filters Benzophenone-3 (BP-3) and Enzacamene (4-MBC) using the freshwater planarian Girardia tigrina

Patricia Rolo, João L.T. Pestana, Diana Campos

UV filters are contaminants of emerging concern, acting as endocrine disruptors, and altering the normal development of living organisms. Due to their lipophilic properties, they accumulate in aquatic sediments, endangering epibenthic organisms such as planarians. We aimed to assess the sensitivity of …

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Endothelial insulin resistance induced by adrenomedullin mediates obesity-associated diabetes

Haaglim Cho, Chien-Cheng Lai, Rémy Bonnavion, Mohamad Wessam Alnouri et autres

Insulin resistance is a hallmark of obesity-associated type 2 diabetes. Insulin's actions go beyond metabolic cells and also involve blood vessels, where insulin increases capillary blood flow and delivery of insulin and nutrients. We show that adrenomedullin, whose plasma levels are increased …

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Effects of naturally sourced bitumen samples from Alberta oil sands region (Canada) on aquatic benthic invertebrates: A case study with Chironomus riparius

Diogo N. Cardoso, João L.T. Pestana, Ana Rita R. Silva, Diana Campos et autres

Athabasca oil sands in Alberta, Canada, are large bitumen deposits and are one of the world's largest petroleum reserves. This research contributes to the growing body of knowledge on the influence of this naturally occurring bitumen on freshwaters. Using laboratory-based exposure studies, …

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Analysis of N‐ and O‐linked site‐specific glycosylation by ion mobility mass spectrometry: State of the art and future directions

Michael J. Girgis, Gregory Petruncio, Paul S. Russo, Steven Peyton et autres

Glycosylation, the major post-translational modification of proteins, significantly increases the diversity of proteoforms. Glycans are involved in a variety of pivotal structural and functional roles of proteins, and changes in glycosylation are profoundly connected to the progression of numerous diseases. Mass spectrometry …

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Responses of Mytilus galloprovincialis in a Multi-Stressor Scenario: Effects of an Invasive Seaweed Exudate and Microplastic Pollution under Ocean Warming

Cristiana Lopes, Andreia C. M. Rodrigues, Sílvia F. S. Pires, Diana Campos et autres

Microplastic pollution, global warming, and invasive species are known threats to marine biota, but the impact of their simultaneous exposure is still not well understood. This study investigated whether the toxic effects posed by the invasive red seaweed Asparagopsis armata exudate (2%) …

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“Ghost” Fragment Ions in Structure and Site-Specific Glycoproteomics Analysis

Diana Campos, Michael J. Girgis, Qiang Yang, Guanghui Zong et autres

Mass spectrometry (MS) can unlock crucial insights into the intricate world of glycosylation analysis. Despite its immense potential, the qualitative and quantitative analysis of isobaric glycopeptide structures remains one of the most daunting hurdles in the field of glycoproteomics. The ability to …

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Toxicity assessment of binary mixtures of BP3 with 4-MBC (UV-filters), and BP3 with DEET (insect repellent) using the aquatic midge Chironomus riparius

Diana Campos, Rui G. Morgado, Ana Rita R. Silva, Ana L. Machado et autres

Personal care products have various organic ultraviolet filters (UV filters) in their composition to increase protection against ultraviolet radiation. Some of these products also contain insect repellents in their formulations. Consequently, these compounds reach freshwater ecosystems, exposing aquatic organisms to a cocktail …

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Nanoplastic exposure inhibits feeding and delays regeneration in a freshwater planarian

Giulia Cesarini, Francesca Coppola, Diana Campos, Iole Venditti et autres

The concentration of nanoplastics (NPs) is expected to increase in aquatic environments thus potentially threatening freshwater organisms through interactions with plastic particles that variously float, circulate in the water column or sink into the benthos. Studies into the mechanisms of any NP …

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“Ghost” fragment ions in structure and site-specific glycoproteomics analysis

Diana Campos, Michael J. Girgis, Qiang Yang, Guanghui Zong et autres

Mass spectrometry (MS) can unlock crucial insights into the intricate world of glycosylation analysis. Despite its immense potential, the qualitative and quantitative analysis of isobaric glycopeptide structures remains one of the most daunting hurdles in the field of glycoproteomics. The ability to …

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Magnetized vermiculite as a tool for the treatment of produced water generated by oil companies: Effects on aquatic organisms before and after treatment

Taís Suelen Viana, Diana Campos, Mariana Bartilotti, F.G. Leite et autres

Produced water (PW) generated by oil companies is a highly impacting waste that contains chemicals such as metals and organic and inorganic compounds. Given its polluting potential, PW requires effective treatment before being discharged into the environment. Conventional treatments have limited efficiency …

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PRÁCTICAS FLOTANTES PARA NO NAUFRAGAR

Taller Flotante, Diana Campos, Ana Julia Bustos