John Tyler Haller

Clevidipine for Nicardipine Resistant Hypertension in Neurocritically Ill Patients

John Tyler Haller, Christian Eslinger, Nicholas Nelson, Anusha Mangalampalli et autres

Acute hypertension is common in acute brain injuries and contributes to increased morbidity and mortality. The optimal agent to manage acute hypertension is unclear, though most critically ill patients in the Neuro Intensive Care Unit (Neuro ICU) are managed with nicardipine as …

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Seizure Rates in Mild and Moderate Traumatic Brain Injury With Intracranial Hemorrhage: A Signal for Prospective Investigation of Seizure Prophylaxis in Moderate TBI

Robert Cortez, Jordan Weinberg, Kristina M. Chapple, Cindy Sullivan et autres

BACKGROUND: Post-traumatic seizures have been shown to occur in patients with traumatic brain injury (TBI). In cases of mild or moderate TBI there is a lack of evidence to guide the use of seizure prophylaxis. The purpose of this study is to …

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Predictive value of thromboelastography with platelet mapping on hematoma expansion in spontaneous intracerebral hemorrhage

Nora Sammani, John J. Radosevich, Sydni Martinez, Travis Lam et autres

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Abstract TP060: Evaluation of the Satety Profile of the Tirofiban Protocol for Select Patients with Acute Ischemic Stroke at a United States Comprehensive Stroke Center

Kevin H. Dang, Josiah Chang, Diane C. McLaughlin, Tracie Schroeder et autres

Background and Purpose: Tirofiban, a glycoprotein IIb/IIIa receptor inhibitor, has been studied as an adjunctive treatment in patients with acute ischemic stroke. In the recent RESCUE BT2 trial in China, intravenous (IV) tirofiban in patients without medium or large vessel occlusions was …

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Implementation of a Nurse-Initiated Protocol to Improve Enteral Medication Administration Documentation in Stroke Patients

John C. Drennan, Tiffany O Sheehan, Tracie Schroeder, John Tyler Haller

ABSTRACT: BACKGROUND: Medication documentation falls under the "7 rights" of medication administration, but strategies to prevent medication administration documentation errors (MADEs) related to route of administration are underreported in the literature. This study aimed to report the outcomes of a nurse-initiated protocol …

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Abstract WMP30: Real World Experience With Tenecteplase on a Mobile Stroke Unit

John Tyler Haller, Tiffany O Sheehan, Daniel Joseph Gonzalez, David Z. Wang et autres

Background: Tenecteplase (TNK) administered on a mobile stroke unit (MSU) has demonstrated superior rates of early reperfusion compared to alteplase. Current guidelines include TNK as a second-tier option for large vessel occlusions as TNK has many benefits, including rapid IV administration and …

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Early Experiences with Intrathecal Administration of Amphotericin B Liposomal Formulation at a Neurosurgical Center

Michael D. Nailor, Kellie J. Goodlet, Omar Gonzalez, John Tyler Haller

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Rapid administration of undiluted loading doses of levetiracetam

Sydni Martinez, Sophia S. Bonnin, John J. Radosevich, John Tyler Haller

OBJECTIVE: Rapid administration of antiseizure medications is a critical concept in the treatment of status epilepticus. Although undiluted levetiracetam (LEV) doses of up to 2500 mg have been evaluated, minimal data exist to support the safety of loading doses up to 4500 …

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1211: EVALUATION OF A WEIGHT-BASED LEVETIRACETAM LOADING DOSE PROTOCOL

John Tyler Haller, Sophia S. Bonnin, John J. Radosevich

Introduction: Status epilepticus (SE) is a common neurological emergency in both emergency departments and intensive care units. The goal of SE management is to rapidly terminate both clinical and electrographic seizure activity. Levetiracetam (LEV) is a favorable second line agent in SE …

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629: RAPID ADMINISTRATION OF UNDILUTED LOADING DOSES OF LEVETIRACETAM

Sydni Martinez, John Tyler Haller, John J. Radosevich, Sophia S. Bonnin

Introduction: Rapid administration of anti-seizure medications is a critical concept in the treatment of status epilepticus. Although undiluted levetiracetam doses of up to 2500 mg have been evaluated, minimal data exists to support the safety of loading doses up to 4500mg. This …

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Rapid administration of undiluted intravenous levetiracetam

John Tyler Haller, Sophia S. Bonnin, John J. Radosevich

OBJECTIVE: Operational delays have the potential to lead to suboptimal time to seizure control during status epilepticus. Levetiracetam (LEV) is an urgent control antiepileptic medication that offers relative lack of adverse effects and ease of monitoring. There are limited data published demonstrating …

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Levetiracetam pharmacokinetics in critically ill patients undergoing renal replacement therapy

Kathryn Chappell, Lauren A. Kimmons, John Tyler Haller, Robert B. Canada et autres

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