Profil bibliographique

Massimo Andreatta

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

141Publications signalées
9644Citations signalées
4Affiliations récentes

Les institutions déclarées

University of GenevaSIB Swiss Institute of BioinformaticsTranslational Research in OncologyCentre for Inflammation Research

Les domaines associés

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkersvaccines and immunoinformatics approachesT-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies Research

Les publications récentes

Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Figure S14 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Experimental design for the induction of an exhausted phenotype in murine OT-I CD8+ T cells, relative expression of co-receptors, exhaustion markers, and TCF7 in murine CD8+ T cells at different time points of the exhaustion protocol, relative RNA expression of Ccl3, Cxcl13, …

0 citations
Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Figure S4 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Relative RNA expression of CCL3 and CRTAM across stimulations of the exhaustion protocol under hypoxic conditions, dysregulated GSEA pathways related to cell cycle progression and apoptosis between singly-stimulated and continuously stimulated T cells under hypoxia, and DEGs in chronically stimulated T cells …

0 citations
Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Figure S3 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Relative expression of exhaustion and activation markers on T cells across stimulations of the exhaustion protocol under normoxic or hypoxic conditions, gating strategy for T cell phenotype annotation, and gating strategy for the analysis of CD39+ and TCF7+ T cells.

0 citations
Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Figure S5 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Maximal respiration, spare respiratory capacity, and ATP-production coupled respiration of T cells across time points and oxygen conditions of the exhaustion protocol, glucose dependence and FAO and AAO capacity in T cells, compensatory glycolysis of T cells, and MitoTracker Deep Red to …

0 citations
Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Figure S2 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Row-normalized UCell-based scores for pathways across different T cell subtypes and correlations among gene signatures related to exhaustion, hypoxia, stress responses, and the proteasome in CD8+ T cells based on single-cell transcriptomic data.

0 citations
Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Tables S1–S5 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Fluorochrome-conjugated antibodies and fluorescent probes used in flow cytometry, primers used for mRNA quantification by quantitative PCR, antibodies used for immunoblotting, primers used for mouse genotyping, and differentially expressed oxidized proteins in T cells treated with TWS119 or DMSO control.

0 citations
Accès ouvert 2026 other OpenAlex

Data from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Abstract Chronic T-cell receptor (TCR) stimulation combined with adverse conditions in the tumor microenvironment (TME), such as hypoxia and nutrient deprivation, frequently results in T-cell exhaustion. Exhausted CD8+ T cells (TEX) experience oxidative stress, which causes an accumulation of oxidized proteins within …

0 citations
Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Figure S13 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Immunoblot analysis of β-catenin in TWS119-treated or DMSO control T cells, NFAT activity assessed by eGFP fluorescence in non-activated or activated TPR cells treated with TWS119 or DMSO control, relative proteasome activity of T cells treated with 20SPA1 or DMSO control, relative …

0 citations
Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Figure S6 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Proinflammatory cytokine production in T cells at different stages of the exhaustion protocol under normoxia or hypoxia, secretion of proinflammatory cytokines after one or four stimulations under hypoxia with standard or reduced levels of glucose, and in vitro cytotoxicity assay comparing the …

0 citations
Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Figure S11 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Relative RNA expression of proteasome subunits and assembly-associated proteins in human memory CD8+ T cells treated with TWS119 or DMSO and differentially expressed E3 ubiquitin ligases and deubiquitinases in TWS119-treated versus DMSO control T cells.

0 citations
Accès ouvert 2026 supplementary-materials OpenAlex

Supplementary Figure S9 from Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity

Ander de Blas, Massimo Andreatta, Asier Antoñana-Vildosola, Paloma Velasco-Beltrán et autres

Normalized RNA expression levels of hypoxia markers and proteasome-related genes in T cells exposed to acute hypoxia or normoxic conditions, proteasome activity in non-activated, singly-stimulated or continuously stimulated T cells under hypoxia, expression of proteasome subunit-encoding genes in murine CD8+ TILs from …

0 citations
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