Fábio Bessa Lima

Neonatal Overnutrition-Induced Adiposity and Glucose Intolerance are Associated with Impaired Lipolytic and Insulin Signaling in Adipose Tissue

Camila F. de Souza, Larissa Rugila S. Stopa, Andressa B. Martins, Ana Luiza Machado Wunderlich et autres

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Optimization of tuned mass damper parameters for axle whine mitigation

Leonardo Rosa Galibern, Henrick Moura Emerick, Fábio Bessa Lima, Daniel Camargo et autres

Vehicle sound quality is crucial in the modern automotive industry due to its impact on quality perception and customer satisfaction. Rear axle whine, a significant noise, vibration and harshness (NVH) concern, originates from the transmission error of hypoid gears in the rear …

Glucocorticoid modulates oxidative and thermogenic function of rat brown adipose tissue and human brown adipocytes

Anaysa Paola Bolin, Flaviane de Fátima Silva, Rafael Barrera Salgueiro, Bruna Araújo dos Santos et autres

Abstract Chronic and excessive glucocorticoid (GC) exposure can cause Cushing's syndrome, resulting in fat accumulation in selected body areas. Particularly in the brown adipose tissue (BAT), GC acts negatively, resulting in whitening of the tissue. We hypothesized that dysregulation of microRNAs by …

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Long-term glucocorticoid infusion impairs epididymal adipocyte metabolism and maturation and affects miR-150–5p actions

Rafael Barrera Salgueiro, Anaysa Paola Bolin, Sandra Andreotti, Ayumi Cristina Medeiros Komino et autres

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Análise do Parâmetro Ru Em Barragens de Terra

Marcos Maia dos Santos, Rosiel Ferreira Leme, Fábio Bessa Lima

RESUMO: Apesar do avanço tecnológico na engenharia, as construções de barragens ainda enfrentam desafios, como na avaliação da estabilidade durante a fase final da construção.Neste estágio, o aumento das cargas durante a elevação do maciço pode gerar excesso de poropressão, ameaçando a …

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Effects of Pinealectomy on the Daily Profile of Circadian Clock and Apoptosis Components in Rat Retroperitoneal Adipose Tissue

Tatienne Neder Figueira-Costa, Rodrigo Antonio Peliciari Garcia, Dayana Silva Gonçalves-Manso, Sandra Andreotti et autres

Visceral adipocytes, typically larger and more pro-inflammatory than subcutaneous adipocytes, are less sensitive to insulin action and more susceptible to apoptosis. Melatonin is an anti-inflammatory, anti-apoptotic, and temporal cue to several tissues, including adipose tissue. The modern lifestyle often involves irregular sleep-wake …

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Intrauterine food restriction impairs the lipogenesis process in the mesenteric adipocytes from low-birth-weight rats into adulthood

Sandra Andreotti, Ayumi Cristina Medeiros Komino, Flaviane de Fátima Silva, Ana Paula Almeida Ramos et autres

Background: Intrauterine food restriction (IFR) during pregnancy is associated with low birth weight (LBW) and obesity in adulthood. It is known that white adipose tissue (WAT) plays critical metabolic and endocrine functions; however, this tissue's behavior before weight gain and obesity into …

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Glucocorticoids contribute to metabolic and liver impairments induced by lactation overnutrition in male adult rats

Camila Franciele de Souza, Larissa Rugila S. Stopa, Andressa Busetti Martins, Ana Luiza Machado Wunderlich et autres

Introduction: Lactation overnutrition is a programming agent of energy metabolism, and litter size reduction leads to the early development of obesity, which persists until adulthood. Liver metabolism is disrupted by obesity, and increased levels of circulating glucocorticoids are pointed as a possible …

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The effect of long-term treatment of glucocorticoid in adipogenesis/turnover in epididymal cells

Rafael Salgueiro, Fábio Bessa Lima

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Dexamethasone-Induced Adipose Tissue Redistribution and Metabolic Changes: Is Gene Expression the Main Factor? An Animal Model of Chronic Hypercortisolism

Flaviane de Fátima Silva, Ayumi Cristina Medeiros Komino, Sandra Andreotti, Gabriela Boltes Reis et autres

Chronic hypercortisolism has been associated with the development of several metabolic alterations, mostly caused by the effects of chronic glucocorticoid (GC) exposure over gene expression. The metabolic changes can be partially explained by the GC actions on different adipose tissues (ATs), leading …

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Whether or Not the Effects of Curcuma longa Supplementation Are Associated with Physical Exercises in T1DM and T2DM: A Systematic Review

Ailton Santos Sena-Júnior, Felipe J. Aidar, Ana Mara de Oliveira e Silva, Charles dos Santos Estevam et autres

Diabetes mellitus is one of the most prevalent chronic diseases in the world; one of its main characteristics is chronic hyperglycemia. Pharmacotherapy and other alternatives such as regular exercise are among the therapeutic methods used to control this pathology and participate in …

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The Influence of Melatonin on the Daily 24-h Rhythm of Putative Reference Gene Expression in White Adipose Tissues

Tatienne Neder Figueira da Costa, Sandra Andreotti, Talita da Silva Mendes de Farias, Fábio Bessa Lima et autres

In adipose tissue, the expression of hundreds of genes exhibits circadian oscillation, which may or may not be affected by circulating melatonin levels. Using control and pinealectomized rats, we investigated the daily expression profile of Actb, Hprt-1, B2m, and Rpl37a, genes that …

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