Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8+ T cells in lymph nodes
Junyun Lai, Cheok Weng Chan, Jesse Armitage, Katherine M. Audsley et autres
5 citationsNature Immunology
C. Scheffler
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16Publications signalées
386Citations signalées
2Affiliations récentes
Institutions déclarées
Domaines associés
CAR-T cell therapy researchImmune Cell Function and InteractionCancer Immunotherapy and BiomarkersAdvanced machining processes and optimizationImmunotherapy and Immune Responses
Publications récentes
Transcriptional regulator SATB1 limits CD8+ T cell population expansion and effector differentiation in chronic infection and cancer
Leonie Heyden, Michael P. Shannon, Lachlan Dryburgh, Marcela L. Moreira et autres
11 citationsNature Immunology
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
Kevin Sek, Amanda X. Y. Chen, Thomas Cole, Jesse Armitage et autres
11 citationsNature Communications
Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery
Amanda X. Y. Chen, Kah Min Yap, Joelle S. Kim, Kevin Sek et autres
78 citationsNature
CRISPR engineering of armored CAR T cells enables tumor restricted payload delivery with enhanced efficacy and safety
Amanda Chen, Kah Min Yap, Joelle S. Kim, Kevin Sek et autres
0 citationsResearch Square
A metabolic pathway for improving adoptive cellular therapy
C. Scheffler, Paul A. Beavis, Phillip K. Darcy
1 citationCancer Cell
DUAL APPLICATION OF CELLPRYME ENHANCES CAR T CELL EFFICACY
C. Scheffler, Jianbin Li, Jiarong Tong, K. Sek et autres
0 citationsCytotherapy
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
Jack D. Chan, C. Scheffler, Isabelle Munoz, Kevin Sek et autres
242 citationsNature
Overexpression of FOXO1 enhances CAR T cell polyfunctionality, metabolic fitness and efficacy against solid tumors
Paul A. Beavis, Phillip K. Darcy, Junyun Lai, Jack D. Chan et autres
0 citationsResearch Square
A2AR eGFP reporter mouse enables elucidation of A2AR expression dynamics during anti-tumor immune responses
Kirsten L. Todd, Junyun Lai, Kevin Sek, Yukuan Huang et autres
9 citationsNature Communications
Characterisation of high strain rate material behaviour for high-speed forming and cutting applications
Marc Tulke, C. Scheffler, Maik Linnemann, Verena Psyk et autres
1 citationJournal of Physics Conference Series
Multi-physics modeling of composite materials for magnetic pulse welding tools
Dmytro Vasiukov, P. Cheng, C. Scheffler, Verena Psyk
0 citationsHAL (Le Centre pour la Communication Scientifique Directe)
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