Tongchuan Li

Clinically relevant variants detected in Chinese children with global developmental delay/intellectual disability: An exome-wide sequencing study

Yimeng Qiao, Nan Lv, Tongchuan Li, Ye Cheng et autres

cn (code pays fourni par la source)

Exome sequencing reveals genetic heterogeneity and clinically actionable findings in children with cerebral palsy

Yangong Wang, Yiran Xu, Chongchen Zhou, Ye Cheng et autres

cn, ca, au, se (code pays fourni par la source)

Exome Sequencing of Young Children with Cerebral Palsy Reveals Considerable Genetic Heterogeneity and Clinically Actionable Findings

Yangong Wang, Yiran Xu, Chongchen Zhou, Ye Cheng et autres

pl, lv, cn, us, au (code pays fourni par la source)

Structure-based discovery of LpxC inhibitors

Jing Zhang, Audrey Chan, Blaise Lippa, Jason B. Cross et autres

us, gb (code pays fourni par la source)

The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy

Dan Bi, Mingjie Chen, Xiaoli Zhang, Honglian Wang et autres

BACKGROUND: The relationship between genetic factors and the development of cerebral palsy (CP) has recently attracted much attention. Polymorphisms in the genes encoding proinflammatory cytokines have been shown to be associated with susceptibility to perinatal brain injury and development of CP. Interleukin-6 …

cn, se, us (code pays fourni par la source)

The association of apolipoprotein E gene polymorphisms with cerebral palsy in Chinese infants

Yiran Xu, Honglian Wang, Yanyan Sun, Qing Shang et autres

cn, us, se (code pays fourni par la source)

Genetic association study of adaptor protein complex 4 with cerebral palsy in a Han Chinese population

Honglian Wang, Yiran Xu, Mingjie Chen, Qing Shang et autres

cn, se (code pays fourni par la source)

The association between GAD1 gene polymorphisms and cerebral palsy in Chinese infants

Sheyu Lin, Tongchuan Li, Dengnan Zhu, Caiyun Ma et autres

Studies suggest that GAD1 gene was a functional candidate susceptibility gene for cerebral palsy (CP). In order to investigate the contribution of GAD1 gene to the etiology of CP in Chinese infants, we carried out a case-control association study between GAD1 gene …

us, cn (code pays fourni par la source)

Association of Interleukin 6 gene polymorphisms with genetic susceptibilities to spastic tetraplegia in males: A case-control study

Mingjie Chen, Tongchuan Li, Sheyu Lin, Dan Bi et autres

cn, se, us (code pays fourni par la source)

In Vitro and In Vivo Characterization of CB-183,315, a Novel Lipopeptide Antibiotic for Treatment of Clostridium difficile

Carmela T. M. Mascio, Lawrence I. Mortin, Karen Howland, Andrew D. G. Van Praagh et autres

CB-183,315 is a novel lipopeptide antibiotic structurally related to daptomycin currently in phase 3 clinical development for Clostridium difficile-associated diarrhea (CDAD). We report here the in vitro mechanism of action, spontaneous resistance incidence, resistance by serial passage, time-kill kinetics, postantibiotic effect, and …

us (code pays fourni par la source)

Daptomycin Antibiotic Lock Therapy in a Rat Model of Staphylococcal Central Venous Catheter Biofilm Infections

Andrew D. G. Van Praagh, Tongchuan Li, Shuxin Zhang, Anu Arya et autres

Antibiotic lock therapy (ALT) is an adjunctive procedure to prevent or treat central venous catheter infections, ensuing catheter-related bacteremia, and catheter-related metastatic infections. Daptomycin is a cyclic lipopeptide that is rapidly bactericidal against methicillin-susceptible and -resistant Staphylococcus aureus. The efficacies of daptomycin …

us (code pays fourni par la source)

Methylenetetrahydrofolate reductase gene polymorphisms and cerebral palsy in Chinese infants

Tongchuan Li, Honglian Wang, Dengna Zhu, Caiyun Ma et autres

cn, gb (code pays fourni par la source)