Kay Tyerman

8481 Reviewing the changes – the training charter reaudit

Dyanne Imo-Ivoke, Kay Tyerman

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Falling enthusiasm for paediatrics in South Korea: it couldn’t happen here. Could it?

Kay Tyerman, Emma M Dyer, Cathryn Chadwick, Jonathan C. Darling et autres

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Fifteen-minute consultation: Empowering children, young people and families through shared decision-making: a practical guide

Arvind Nagra, Isabella Darshani Fuller, Gary Connett, B. C. Reynolds et autres

Shared decision-making (SDM) is a collaborative approach to healthcare decision-making that involves patients and healthcare professionals working together to make decisions that are informed by the best available medical evidence, as well as the patient's values, preferences and goals. The importance of …

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Description and Cross-Sectional Analyses of 25,880 Adults and Children in the UK National Registry of Rare Kidney Diseases Cohort

Katie Wong, David Pitcher, Fiona Braddon, Lewis Downward et autres

Introduction The National Registry of Rare Kidney Diseases (RaDaR) collects data from people living with rare kidney diseases across the UK, and is the world's largest rare kidney disease registry. We present the clinical demographics and renal function of 25,880 prevalent patients …

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Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort

Katie Wong, David Pitcher, Fiona Braddon, Lewis Downward et autres

Background Individuals with rare kidney diseases account for 5–10% of people with chronic kidney disease, but constitute more than 25% of patients receiving kidney replacement therapy. The National Registry of Rare Kidney Diseases (RaDaR) gathers longitudinal data from patients with these conditions, …

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896 Use of renal biopsy in the diagnosis and management of paediatric lupus nephritis with outcome analysis in UK tertiary centre

Thomas Reilly, Joseph Hardwick, Jessica Presky, Kay Tyerman et autres

Objectives Lupus Nephritis (LN) occurs in 50–60% of children with Systemic Lupus Erythematous1 and it is often evident at presentation, with accrued parenchymal damage.2 European guidance on the management of LN was updated in 2019.2 Renal biopsy is the gold standard investigation, …

A Case of Paediatric Anti-Glomerular Basement Membrane Disease Associated with Thrombotic Thrombocytopenic Purpura

Joseph McAllister, Pradeep Nagisetty, Kay Tyerman

Anti-GBM disease is a rare vasculitis that causes rapid progressive glomerulonephritis and pulmonary haemorrhage. It is usually an adult diagnosis with isolated paediatric cases reported. Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy mainly affecting adults that causes multiorgan ischaemia, microangiopathic …

Economic Evaluation of Using Daily Prednisolone versus Placebo at the Time of an Upper Respiratory Tract Infection for the Management of Children with Steroid-Sensitive Nephrotic Syndrome: A Model-Based Analysis

Nafsika Afentou, Emma Frew, Samir Mehta, Natalie Ives et autres

BACKGROUND: Childhood steroid-sensitive nephrotic syndrome is a frequently relapsing disease with significant short- and long-term complications, leading to high healthcare costs and reduced quality of life for patients. The majority of relapses are triggered by upper respiratory tract infections (URTIs) and evidence …

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Advanced chronic kidney disease among UK children

Lucy Plumb, Winnie Magadi, Anna Casula, B. C. Reynolds et autres

The UK Renal Registry currently collects information on UK children with kidney failure requiring long-term kidney replacement therapy (KRT), which supports disease surveillance and auditing of care and outcomes; however, data are limited on children with chronic kidney disease (CKD) not on …

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571 COVID-19: Experiences of lockdown and support needs in children and young adults with kidney conditions

Yincent Tse, Anne‐Sophie Darlington, Kay Tyerman, Dean Wallace et autres

Background During the initial COVID-19 pandemic, young United Kingdom (UK) kidney patients underwent lockdown and those with increased vulnerabilities socially isolated or ‘shielded’ at home. The experiences, information needs, decision-making and support needs of children and young adult (CYA) patients or their …

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1697 Five years of thinking kidneys: reviewing paediatric AKI services

Joseph B. McAllister, Kay Tyerman, Amanda Newnham, Hitesh Prajapati et autres

Background It has been five years since the ‘Think Kidney’s’ campaign to improve recognition and management of acute kidney injury (AKI). Whilst there have been rapid advances in AKI services in adult medicine, the progress in paediatricst has been much slower and …

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UK experience of ofatumumab in recurrence of focal segmental glomerulosclerosis post-kidney transplant

B. C. Reynolds, Angela Lamb, Caroline Jones, Pallavi Yadav et autres

Abstract Background Steroid-resistant nephrotic syndrome (SRNS), commonly caused by focal segmental glomerulosclerosis (FSGS), is associated with progression to stage 5 chronic kidney disease, requirement for kidney replacement therapy and a risk of disease recurrence post-kidney transplantation. Ofatumumab (OFA) is a fully humanised …

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