Xia Chi

Exploring the relationship between auditory processing characteristics and cognition in preschool children with developmental language disorder based on fNIRS

Wenmin Wang, Panting Liu, Bingzi Hao, Jia Zhou et autres

BACKGROUND: Auditory processing (AP) is a fundamental function in speech signal processing. The ability to process speech signals in noisy environments is commonly used to assess AP capabilities. Research on the AP characteristics in Chinese children remains scarce, and the relationship between …

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Secular Trends in Anthropometric Measures Among Preschool Children in Nanjing, China: A 30-Year Analysis (1995–2025)

Le Chen, Ling xia Pang, Chun Zhu, Fang Yan Huang et autres

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Neural processing of speech in noise recognition in preschool children with different auditory processing abilities: a fNIRS study

Panting Liu, Wenmin Wang, Jia Zhou, H J Lin et autres

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Safety and user perception of general-purpose large language models in pediatric healthcare: Evaluations of ChatGPT by doctors and parents

Jing Tan, Lin Wang, Guanghai Wang, Y S Yang et autres

Background/Objective Although the internet has broadened access to medical resources, concerns persist regarding the quality and accuracy of available content. ChatGPT, a general-purpose large language model, may help bridge this gap. This study evaluates its safety and user perception in addressing pediatric …

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Prenatal exposure to hyperglycemia and child growth trajectories in the first 3 years of life: a prospective birth cohort

Yiyuan Chen, Xia Chi, Shu‐Ting Wu, Jing Wei et autres

BACKGROUND: Infants exposed to hyperglycemia in pregnancy (HIP) in utero are known to have higher risks of macrosomia at birth and obesity in adulthood, but longitudinal growth patterns in early childhood remain poorly characterized. This study aimed to examine HIP-associated differences in …

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Deficiency of Kdm1a Induces Locomotor Abnormalities and Learning and Memory Deficits in Zebrafish Larvae

Qu Xu, Qin Hong, Jiansheng Zhu, Xia Chi

Background: Lysine-Specific Demethylase 1A (Kdm1a) is the first discovered histone lysine-specific demethylase, and mutations in kdm1a have been detected in neurodevelopmental disorders. However, the effect of kdm1a on neurobehaviors and the underlying mechanisms remain largely unknown. Methods: In this study, kdm1a deficient …

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Maternal cholesterol deficiency predisposes congenital heart defects risk

Yayun Gu, Jimiao Gao, Hong Lv, Yan Zhou et autres

Abstract The relationship between maternal cholesterol deficiency and the risk of congenital heart defects (CHDs) in offspring is not fully understood. In a birth cohort study of 5041 family trios, we found that low maternal cholesterol levels were significantly associated with an …

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Platelet-to-Neutrophil Ratio and Efficacy of Remote Ischemic Conditioning in Acute Ischemic Stroke

Yu Cui, Ling-Yun Cui, Xia Chi, Qi Wang et autres

BACKGROUND: Remote ischemic conditioning (RIC) has been proven to improve neurologic function after stroke in RICAMIS trial. Aggravated thrombosis and inflammatory through interaction between platelet and immune cells affected the prognosis of stroke. We conducted an exploratory secondary analysis of RICAMIS to …

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Prenatal exposure to hyperglycemia and child growth trajectories in the first three years of life: a prospective birth cohort

Yiyuan Chen, Xia Chi, Shuting Wu, Jing Wei et autres

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Vitamin A attenuates PFOS-induced neurotoxicity and alters early proximity patterns to conspecifics in zebrafish larvae

Peiyun Jiang, Jingyu Wang, Xiaoying Wang, Li Zou et autres

Introduction: Perfluorooctane sulfonic acid (PFOS), a persistent perfluoroalkyl substance with ubiquitous environmental distribution and bioaccumulative potential, has raised significant public health concerns due to its association with neurodevelopmental disorders. This study investigates vitamin A's neuroprotective capacity against PFOS-induced toxicity, particularly focusing on …

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[Family socioeconomic status and children's reading fluency: the chain mediating role of family reading environment and children's living and learning styles].

Wenxin Hu, Lei Zhang, Cai Wang, Ziyue Wang et autres

OBJECTIVES: To study the impact of family socioeconomic status on children's reading fluency and the chain mediation effect of family reading environment and children's living and learning styles in this relationship. METHODS: A total of 473 children from grades 2 to 6 …

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Subgroup analysis of imaging scans, invasive examinations and prognosis in mild-to-moderate isolated foetal cerebral ventriculomegaly: a retrospective study in China

Chun Lian Yang, Xia Chi, Yan Wang, Cuiping Zhang et autres

OBJECTIVE: This study aimed to analyse the causes of foetal mild-to-moderate isolated ventriculomegaly (IVM) and to evaluate the prognosis of neurological development in surviving children in different subgroups. METHODS: We retrospectively studied mild-to-moderate IVM diagnosed by prenatal ultrasound scans in different subgroups …

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