Roman Ganzer

Patient-Reported Outcomes on Quality of Life and Psychological Distress After Focal High-Intensity Focused Ultrasound for Prostate Cancer: Prospective Multicenter Study

Toni Franz, Cornelia Hartung, Roman Ganzer, Sigrun Holze et autres

Background: Focal high-intensity focused ultrasound (HIFU) is an emerging tissue-preserving treatment for localized prostate cancer (PCa) that aims to reduce functional impairment and psychological burden while maintaining oncological safety. Although its clinical use is increasing, prospective data on health-related quality of life …

de (code pays fourni par la source)

Patient-Reported Outcomes on Quality of Life and Psychological Distress After Focal High-Intensity Focused Ultrasound (HIFU) for Prostate Cancer: A Prospective Multicenter Study (Preprint)

Toni Franz, Cornelia Hartung, Roman Ganzer, Sigrun Holze et autres

BACKGROUND Focal high-intensity focused ultrasound (HIFU) is an emerging tissue-preserving treatment for localized prostate cancer (PCa) that aims to reduce functional impairment and psychological burden while maintaining oncological safety. Although its clinical use is increasing, prospective data on health-related quality of life …

Evaluation of the TARGET score for MRI-based detection of prostate cancer recurrence in patients treated with HIFU hemiablation

Constantin Ehrengut, Nilüfer Deniz Alberalar, Toni Franz, Lars‐Christian Horn et autres

PURPOSE: To evaluate diagnostic performance and inter-reader agreement of the Transatlantic Recommendations for Prostate Gland Evaluation with MRI after Focal Therapy (TARGET). METHODS: This retrospective, multi-center study included patients who underwent high-intensity focused ultrasound (HIFU) hemiablation for localized prostate cancer (PCa), with …

de (code pays fourni par la source)

Urologische Erkrankungen in der proktologischen Ambulanz

Benedikt Buchner, A. Ommer, Christian Frei, Roman Ganzer

de (code pays fourni par la source)

Supplementary Tables S1-S4 from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes

Miodrag Gužvić, Bernhard Braun, Roman Ganzer, Maximilian Burger et autres

Supplementary Tables S1-S4. Supplementary Table S1 - Sequences of primers used in this study. Supplementary Table S2 - Detection rate of EpCAM+ cells and the number of isolated and analyzes EpCAM+ single cells. Supplementary Table S3 - Numbers and frequencies of samples …

Legends for Supplementary Figures S1-S11 from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes

Miodrag Gužvić, Bernhard Braun, Roman Ganzer, Maximilian Burger et autres

Legends for Supplementary Figures S1-S11. Supplementary Figure S1 - Workflow employed in this study. Supplementary Figure S2 - Photographs of cell lines stained with isotype antibodies. Supplementary Figure S3 - Box-plot representing BM cell numbers before and after immunomagnetic selection, number of …

Data from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes

Miodrag Gužvić, Bernhard Braun, Roman Ganzer, Maximilian Burger et autres

Abstract Bone is the most frequent site of metastasis in prostate cancer and patients with bone metastases are deemed incurable. Targeting prostate cancer cells that disseminated to the bone marrow before surgery and before metastatic outgrowth may therefore prevent lethal metastasis. This …

de (code pays fourni par la source)

Supplementary Figures S1-S11 from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes

Miodrag Gužvić, Bernhard Braun, Roman Ganzer, Maximilian Burger et autres

Supplementary Figures S1-S11. Supplementary Figure S1 - Workflow employed in this study. Supplementary Figure S2 - Photographs of cell lines stained with isotype antibodies. Supplementary Figure S3 - Box-plot representing BM cell numbers before and after immunomagnetic selection, number of screened cells …

Data from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes

Miodrag Gužvić, Bernhard Braun, Roman Ganzer, Maximilian Burger et autres

Abstract Bone is the most frequent site of metastasis in prostate cancer and patients with bone metastases are deemed incurable. Targeting prostate cancer cells that disseminated to the bone marrow before surgery and before metastatic outgrowth may therefore prevent lethal metastasis. This …

de (code pays fourni par la source)

Legends for Supplementary Figures S1-S11 from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes

Miodrag Gužvić, Bernhard Braun, Roman Ganzer, Maximilian Burger et autres

Legends for Supplementary Figures S1-S11. Supplementary Figure S1 - Workflow employed in this study. Supplementary Figure S2 - Photographs of cell lines stained with isotype antibodies. Supplementary Figure S3 - Box-plot representing BM cell numbers before and after immunomagnetic selection, number of …

Supplementary Figures S1-S11 from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes

Miodrag Gužvić, Bernhard Braun, Roman Ganzer, Maximilian Burger et autres

Supplementary Figures S1-S11. Supplementary Figure S1 - Workflow employed in this study. Supplementary Figure S2 - Photographs of cell lines stained with isotype antibodies. Supplementary Figure S3 - Box-plot representing BM cell numbers before and after immunomagnetic selection, number of screened cells …

Supplementary Methods from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes

Miodrag Gužvić, Bernhard Braun, Roman Ganzer, Maximilian Burger et autres

Supplementary Methods. Processing of BM samples, Staining of BM samples and cell lines, Screening of BM and isolation of single cells and cell pools, WTA, WGA, and Establishing of conditions for specific end-point PCR.