Danny Lam

Dexamethasone-loaded platelet-inspired nanoparticles improve intracortical microelectrode recording performance

Longshun Li, Aniya Hartzler, Dhariyat M. Menendez-Lustri, Jichu Zhang et autres

Long-term robust intracortical microelectrode (IME) neural recording quality is negatively affected by the neuroinflammatory response following microelectrode insertion. This adversely impacts brain-machine interface (BMI) performance for patients with neurological disorders or amputations. Recent studies suggest that the leakage of blood-brain barrier (BBB) …

us (code pays fourni par la source)

Evaluation of gold helical microwire structure electrode for long-term rodent nerve stimulation

Danny Lam, Kevin Yang, Derrick X. Liu, Anna Lauricella et autres

Abstract Objective. The development of electrodes for chronic peripheral nerve stimulation faces several challenges, including complex compositions, intricate manufacturing processes, and high costs associated with the availability and fabrication of suitable materials. These limitations hinder the accessibility and feasibility of producing effective …

us (code pays fourni par la source)

Dexamethasone-loaded platelet-inspired nanoparticles improve intracortical microelectrode recording performance

Andrew J. Shoffstall, Longshun Li, Aniya Hartzler, Dhariyat M. Menendez-Lustri et autres

us (code pays fourni par la source)

Epidural spinal cord recordings (ESRs): sources of neural-appearing artifact in stimulation evoked compound action potentials

Ashlesha Deshmukh, Megan L. Settell, Kevin Cheng, Bruce E. Knudsen et autres

Abstract Objective. Evoked compound action potentials (ECAPs) measured during epidural spinal cord stimulation (SCS) can help elucidate fundamental mechanisms for the treatment of pain and inform closed-loop control of SCS. Previous studies have used ECAPs to characterize neural responses to various neuromodulation …

us (code pays fourni par la source)

Correction: The role of spinal cord neuroanatomy in the variances of epidural spinal recordings

Danny Lam, Justin Chin, Meagan Brucker-Hahn, Megan L. Settell et autres

us (code pays fourni par la source)

The role of spinal cord neuroanatomy in the variances of epidural spinal recordings

Danny Lam, Justin Chin, Meagan Brucker-Hahn, Megan L. Settell et autres

BACKGROUND: Spinal cord stimulation (SCS) has demonstrated multiple benefits in treating chronic pain and other clinical disorders related to sensorimotor dysfunctions. However, the underlying mechanisms are still not fully understood, including how electrode placement in relation to the spinal cord neuroanatomy influences …

us (code pays fourni par la source)

Corrigendum to “Platelets and Hemostatic Proteins are Co-Localized with Chronic Neuroinflammation Surrounding Implanted Intracortical Microelectrodes” [Acta Biomaterialia. Volume 166, August 2023, Pages 278-290]

Danny Lam, Anisha Javadekar, Nirav Patil, Marina H. Yu et autres

us (code pays fourni par la source)

Epidural Spinal Cord Recordings (ESRs): Sources of Artifact in Stimulation Evoked Compound Action Potentials

Ashlesha Deshmukh, Megan L. Settell, Kevin Cheng, Bruce E. Knudsen et autres

Introduction: Evoked compound action potentials (ECAPs) measured using epidural spinal recordings (ESRs) during epidural spinal cord stimulation (SCS) can help elucidate fundamental mechanisms for the treatment of pain, as well as inform closed-loop control of SCS. Previous studies have used ECAPs to …

us, se, it (code pays fourni par la source)

An Open-Source 3D-Printed Hindlimb Stabilization Apparatus for Reliable Measurement of Stimulation-Evoked Ankle Flexion in Rat

Danny Lam, Madeline Lindemann, Kevin Yang, Derrick X. Liu et autres

Currently there are numerous methods to evaluate peripheral nerve stimulation interfaces in rats, with stimulation-evoked ankle torque being one of the most prominent. Commercial rat ankle torque measurement systems and custom one-off solutions have been published in the literature. However, commercial systems …

us (code pays fourni par la source)

ID: 213423 Changes in Evoked Responses During Epidural Spinal Cord Stimulation Generated by Minimal Movement of Leads

Danny Lam, Kang Shu, Yuichiro Nishiyama, Ben Romanauski et autres

ID: 217533 An Injectable Electrode Enables Chronic Wireless Stimulation of the Rodent Sciatic Nerve

Derrick Liu, David Valencia, Sachit Kshatriya, J. Conard et autres

ID: 212311 Imaging the Neural Micro-Anatomy of the Swine Spinal Cord

Aniruddha Upadhye, Megan L. Settell, Chaitanya Kolluru, Ashlesha Deshmukh et autres