A Synthetic mRNA Cell Reprogramming Method Using CYCLIN D1 Promotes DNA rEpair, Generating Improved Genetically Stable Human Induced Pluripotent Stem Cells
Ana Belén Alvarez-Palomo, Jordi Requena-Osete, Raúl Delgado‐Morales, Victoria Moreno‐Manzano et autres
A key challenge for clinical application of induced pluripotent stem cells (iPSC) to accurately model and treat human pathologies depends on developing a method to generate genetically stable cells to reduce long-term risks of cell transplant therapy. Here, we hypothesized that CYCLIN …
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Stem Cells