Lida Ren

Clean Intermittent Catheterization Before Initial Urodynamics Reduces Urinary Tract Infection and Improves Bladder Storage Function in Acute/Subacute Spinal Cord Injury: A Prospective cohort study

Mengyang Zhang, Ye Chen, Lida Ren, Dongxu Lin et autres

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Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu et autres

Abstract Neurogenic bladder (NB)‐induced fibrosis is the major cause of irreversible bladder dysfunction, yet the underlying mechanisms remain undefined. Here, leveraging single‐cell RNA sequencing, the fibrotic landscape of NB is delineated and a distinct integrin α8 (Itga8) ⁺ fibroblast population. The Itga8⁺ …

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Underactive Bladder and Detrusor Underactivity: New Advances and Prospectives

Jiaxin Wang, Lida Ren, Xinqi Liu, Jihong Liu et autres

Underactive bladder (UAB) is a prevalent but under-researched lower urinary tract symptom that typically occurs alongside detrusor underactivity (DU). Unlike UAB, DU is a urodynamic diagnosis which the International Continence Society (ICS) defines as "a contraction of reduced strength and/or duration, resulting …

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Transcriptomics Reveals Molecular Features of the Bilateral Pelvic Nerve Injury Rat Model of Detrusor Underactivity

Jiaxin Wang, Lida Ren, Xinqi Liu, Wenchao Xu et autres

The pathogenesis of detrusor underactivity (DU) is unclear, and the available therapeutic effects are unsatisfactory. We propose to find key molecules and pathways related to DU based on transcriptome sequencing. A rat model of bilateral pelvic nerve injury (BPNI) was established. Bladder …

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Shared-probe system: An accurate, low-cost and general enzyme-assisted DNA probe system for detection of genetic mutation

Lida Ren, Zhihao Ming, Wei Zhang, Yangwei Liao et autres

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Short‐DNA Specific Blocker PCR for Efficient and Simple Enrichment of Cell Free Fetal DNAs with Short Lengths

Yangwei Liao, Xiaofeng Tang, Zhihao Ming, Lida Ren et autres

Main observation and conclusion As an innate characteristic, DNA length has attracted more and more attention. The length of some important biomarkers such as ctDNA (Circulating tumor DNA) and cffDNA (Cell free fetal DNA) is shorter than that of cell‐free DNA. Researchers …

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Bladder Replacement Therapy

Xinqi Liu, Jiaxin Wang, Lida Ren, Qing Dong Ling

The bladder, as a vital organ of the urinary system, facilitates urine storage and micturition. The bladder can store urine under low pressure, sense volume changes, and coordinate with the urethral sphincter to ensure autonomous and efficient urination and bladder emptying. However, …

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