Maria Grazia Ceraolo

Photonic Immunosorbent Assay PHISA for specific detection of label-free biomolecules

Maria Grazia Ceraolo, Stefano Ferretti, Silvia Gentilini, Angela Capocefalo et autres

Detecting small amounts of specific biomolecules with high precision is a cornerstone of environmental monitoring, medical diagnostics, and biochemical research. Consolidated biochemical immunoassays offer established protocols and high reliability but suffer from complex procedures, expensive reagents, invasive labeling, and prolonged timescales. We …

A comprehensive toolkit for manipulation and analysis of sprouting capillary networks based on magnetic ordering of multiple EC-coated microcarriers and their use in tissue modelling and drug testing

Katarzyna Olga Rojek, Antoni Wrzos, Fabio Maiullari, Konrad Gizynski et autres

, in angiogenesis/anastomosis research as well as high-throughput drug testing including personalized therapies.

pl, it (code pays fourni par la source)

Author response for "A comprehensive toolkit for manipulation and analysis of sprouting capillary networks based on magnetic ordering of multiple EC-coated microcarriers and their use in tissue modelling and drug testing"

Katarzyna Olga Rojek, Antoni Wrzos, Fabio Maiullari, Konrad Gizynski et autres

Photonic immunosorbent assay PHISA for specific detection of label-free biomolecules

Maria Grazia Ceraolo, Stefano Ferretti, Silvia Gentilini, Angela Capocefalo et autres

Detecting small amounts of specific biomolecules with high precision is a cornerstone of environmental monitoring, medical diagnostics, and biochemical research. Consolidated biochemical immunoassays offer established protocols and high reliability but suffer from complex procedures, expensive reagents, invasive labeling, and prolonged timescales. We …

it, cz, Afrique du Sud (code pays fourni par la source)

Author response for "A comprehensive toolkit for manipulation and analysis of sprouting capillary networks based on magnetic ordering of multiple EC-coated microcarriers and their use in tissue modelling and drug testing"

Katarzyna Olga Rojek, Antoni Wrzos, Fabio Maiullari, Konrad Gizynski et autres

CSPG4.CAR-T Cells Modulate Extracellular Matrix Remodeling in DMD Cardiomyopathy

Maria Grazia Ceraolo, Marika Milan, Nicole Fratini, Elisa Pesce et autres

Targeting fibrosis in Duchenne muscular dystrophy (DMD)-associated cardiomyopathy is a critical outstanding clinical issue, as cardiac failure remains a leading cause of death despite advances in supportive care. This study evaluates the therapeutic efficacy of CSPG4-targeted chimeric antigen receptor (CAR) T cells …

us (code pays fourni par la source)

CSPG4.CAR-T Cells Modulate Extracellular Matrix Remodeling in DMD Cardiomyopathy

Maria Grazia Ceraolo, Marika Milan, Nicole Fratini, Raffaello Viganò et autres

Targeting fibrosis in Duchenne muscular dystrophy (DMD)-associated cardiomyopathy is a critical outstanding clinical issue, as cardiac failure remains a leading cause of death despite advances in supportive care. This study evaluates the therapeutic efficacy of CSPG4-targeted chimeric antigen receptor (CAR) T cells …

it, us, pl (code pays fourni par la source)

Modeling breast cancer dynamics through modulable small Vessel Environment Bioreactor (sVEB)

Fabio Maiullari, Maria Grazia Ceraolo, Dario Presutti, Nicole Fratini et autres

ABSTRACT The development of advanced in vitro systems to replicate vascularized tissue environments is critical for studying cancer progression, immune interactions, and therapeutic responses. Traditional models often lack physiological perfusion, scale flexibility, and compatibility with complex microenvironments, limiting their translational impact. The …

it, pl (code pays fourni par la source)

Engineering of interconnected microcapillary networks at the mesoscale via magnetic assembly of endothelial-cell ‘seeds’

Katarzyna O. Rojek, Antoni Wrzos, Fabio Maiullari, Konrad Giżyński et autres

ABSTRACT Despite significant developments in endothelial-cell (EC) manipulation techniques, a proper in vitro model of a functional microvasculature with controlled local interconnectivity under well-defined global architecture is still lacking. Here, we report the generation of such controlled multi-scale vascular net-works via manipulation …

pl, it (code pays fourni par la source)

Mimicking the Dystrophic Cardiac Extracellular Environment through DystroGel

Maila Chirivì, Fabio Maiullari, Marika Milan, Maria Grazia Ceraolo et autres

Advances in understanding the mechanisms behind genetic diseases like Duchenne muscular dystrophy (DMD) underscore the critical role of the extracellular matrix (ECM) composition in disease progression. Effective in vitro models must replicate the intercellular relationships and physicochemical properties of native ECM to …

it, de, pl (code pays fourni par la source)

Bioactive Hydrogel Supplemented with Stromal Cell-Derived Extracellular Vesicles Enhance Wound Healing

Matteo Galbiati, Fabio Maiullari, Maria Grazia Ceraolo, Salma Bousselmi et autres

Background/Objectives: Skin regeneration is a rapidly advancing field with significant implications for regenerative medicine, particularly in treating wounds and burns. This study explores the potential of hydrogels functionalized with fibroblast-derived extracellular vesicles (EVs) to enhance skin regeneration in vivo. Being immunoprivileged, EVs …

it, pl (code pays fourni par la source)

Modeling Breast Cancer Dynamics Through Modulable Small Vessel Environment Bioreactor (sVEB)

Fabio Maiullari, Maria Grazia Ceraolo, Dario Presutti, Nicole Fratini et autres

us, it, pl (code pays fourni par la source)