Incident coronary heart disease, residual risk and traditional cardiovascular risk factors in the community: The role of the lipid-inflammatory axis

Résumé fourni par la source

Background and aims : Coronary heart disease (CHD) occurs even in individuals classified as “low-risk” by traditional cardiovascular risk factors (CVRFs). We aimed to investigate whether the combinations of high-sensitivity C-reactive protein (hsCRP), lipoprotein (a) (Lp(a)), or triglycerides (TGs) would modulate relative and absolute CHD risk within a low-risk population. Methods : A total of 63,740 individuals free of CHD at baseline were included. Participants were stratified according to CVRF burden at baseline: 0/1 vs. ≥2 CVRFs. Biomarkers were analyzed dichotomously: hsCRP (<vs.≥2 mg/L), Lp(a) (<vs.≥ 90 th percentile), TGs (

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.