Impact of SARS-CoV-2 Pandemic on Neuroinfectious Etiology in the Lazio Region: Evidence from Laboratory-Based Surveillance Analysis
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Le résumé fourni par la source
The mitigation measures adopted to reduce the spread of COVID-19 have not only impacted the transmission of respiratory infections but also other infectious diseases. In this study, we explored the effect of the pandemic on the epidemiology of Central Nervous System (CNS) infections by conducting a retrospective analysis of diagnostic data obtained from cerebrospinal fluids (CSFs) collected before, during, and after the pandemic from patients with acute-suspected neuro-infectious syndrome. The samples were analyzed using a meningitis/encephalitis molecular syndromic panel. A total of 4203 CSFs were split into three groups: pre-pandemic (August 2018–February 2020), pandemic (March 2020–March 2022) and post-pandemic (April 2022–March 2024). Each pathogen was statistically assessed individually, comparing one group vs. another. Results showed that viral pathogens were the most frequently detected across all groups; however, Streptococcus pneumoniae was the single most identified pathogen. Comparison of the pre-pandemic and pandemic groups by statistical analysis showed a significant reduction in neuro-infections caused by enterovirus, S. pneumoniae and N. meningitidis, while the other pathogens were not affected. In conclusion, a reduction in CNS infections caused by respiratory and close-contact-transmitted pathogens, including both viral and bacterial agents, was observed during the period when COVID-19 containment measures were in effect.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Impact of SARS-CoV-2 Pandemic on Neuroinfectious Etiology in the Lazio Region: Evidence from Laboratory-Based Surveillance Analysis
- Date Crossref
- 12/08/2026
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani pays non établi dans la noticeÉtablissement de santé
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Center for Prevention and Treatment of Infections pays non établi dans la noticeStructure de recherche
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Laboratory of Virology and Laboratories of Biosecurity pays non établi dans la noticeStructure de recherche
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Clinical Epidemiology and Biostatistics Unit pays non établi dans la noticeÉtablissement de santé
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National Institute for Infectious Diseases ‘Lazzaro Spallanzani’—IRCCS Regional Service for Surveillance and Control of Infectious Diseases (SERESMI) pays non établi dans la noticeStructure de recherche
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Clinical Department pays non établi dans la noticeÉtablissement de santé
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani, Center for Prevention and Treatment of Infections et Laboratory of Virology and Laboratories of Biosecurity, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.