Global Associations of Sodium Intake With Dementia Prevalence From 2010 to 2021 by Sex: A Longitudinal Ecological Study
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Le résumé fourni par la source
Objective Dementia is a major global health challenge, and its prevalence differs according to sex. Dietary sodium intake is considered a modifiable risk factor of dementia. However, the sex-related associations between sodium intake and dementia prevalence based on global data have not been examined. Therefore, this ecological study aimed to analyze the cross-sectional and longitudinal association between sodium intake and dementia prevalence by sex from 2010 to 2021 with the aim of comprehensively elucidating the relationship between sodium intake and dementia. Methods This longitudinal ecological study analyzed data from 151 countries with populations exceeding one million for which relevant data were available (totaling 1,812 country-year observations) to examine associations between baseline (2010) sodium intake and the 12-year trajectory (2010–2021) of dementia prevalence. Data on national-level estimated average habitual sodium intake, dementia prevalence, and covariates were obtained from internationally available databases. A generalized linear model controlled for all available covariates in this study was used for the cross-sectional model in 2010, and a linear mixed model controlled for all available covariables in this study was used for longitudinal analysis from 2010 to 2021. The risk ratio (RR) was estimated based on the difference between the logarithms of sodium intake and dementia prevalence. Results In the 2010 cross-sectional analysis and 2010–2021 longitudinal analysis, estimated national-level average habitual sodium intake was positively associated with dementia prevalence in both men and women. At a national-level estimated average habitual sodium intake of 4.0 g/day, the RR (95% CI) for dementia prevalence, relative to the reference, was 1.09 (1.03–1.16) for men and 1.07 (1.00–1.13) for women compared to the reference. Five countries (3.3%) had sodium intake of ≥4.0 g/day for both men and women. Conclusions Higher sodium intake is associated with higher sex-stratified dementia prevalence worldwide compared to lower sodium intake.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Global Associations of Sodium Intake With Dementia Prevalence From 2010 to 2021 by Sex: A Longitudinal Ecological Study
- Date Crossref
- 01/06/2026
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Tsu City College Department of Food and Nutrition pays non établi dans la noticeUniversité ou école supérieure
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Nagoya University of Arts and Sciences Institute of Health and Nutrition pays non établi dans la noticeUniversité ou école supérieure
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Doshisha Women's College of Liberal Arts Department of Food Science and Nutrition pays non établi dans la noticeUniversité ou école supérieure
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National Institute of Biomedical Innovation pays non établi dans la noticeStructure de recherche
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Heisei College of Health Sciences Department of Nursing pays non établi dans la noticeUniversité ou école supérieure
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Hamamatsu University Hospital Clinical Nutrition Unit pays non établi dans la noticeÉtablissement de santé
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Kanagawa University of Human Services pays non établi dans la noticeUniversité ou école supérieure
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Japanese Red Cross Nagoya Daiichi Hospital pays non établi dans la noticeÉtablissement de santé
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National Institutes of Biomedical Innovation Center for Nutritional Epidemiology and Policy Research pays non établi dans la noticeStructure de recherche
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Asuke Hospital Aichi Prefectural Welfare Federation of Agricultural Cooperatives Department of Nutrition pays non établi dans la noticeÉtablissement de santé
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Faculty of Health and Social Services pays non établi dans la noticeUniversité ou école supérieure
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Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital Department of Nutrition pays non établi dans la noticeÉtablissement de santé
Department of Food and Nutrition — Tsu City College, Institute of Health and Nutrition — Nagoya University of Arts and Sciences et Department of Food Science and Nutrition — Doshisha Women's College of Liberal Arts, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.