Unraveling the alteration of chemical compositions in Cordyceps and its host larvae using mass spectrometry imaging
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Le résumé fourni par la source
Cordyceps (Chinese caterpillar fungus) is a precious medicinal and edible fungus-larva complex that is naturally formed in a specific environment. However, limited data have been reported on spatial alterations in the lipidome and metabolome of larvae before and after entomopathogenic fungal infection. In this work, changes in chemical compositions and their spatial distribution patterns between host larva and the fungus-larva complex were visualized and characterized using matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI MSI). Liquid chromatography-mass spectrometry (LC-MS) was performed to support MALDI MSI results. Our work revealed the single dominant distribution of many compounds in the host larva, as well as stroma and sclerotium of Cordyceps. Based on further analysis, the heterogeneous distribution of certain lipid classes across the host larva, stroma and sclerotium of Cordyceps was revealed, reflecting key lipid metabolic events, such as assimilation, dissimilation, and synthesis of derivatives. Small metabolites were also detected, and an increase in both the amount and the kinds was observed from larvae to Cordyceps.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Unraveling the alteration of chemical compositions in Cordyceps and its host larvae using mass spectrometry imaging
- Date Crossref
- 01/01/2026
- Éditeur
- Royal Society of Chemistry (RSC)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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China Pharmaceutical University pays non établi dans la noticeUniversité ou école supérieure
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State Administration of Traditional Chinese Medicine of the People's Republic of China pays non établi dans la noticeOrganisme public
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State Key Laboratory of Natural Medicines and School of Traditional Chinese Pharmacy pays non établi dans la noticeUniversité ou école supérieure
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Key Laboratory of State Administration of Traditional Chinese Medicine pays non établi dans la noticeStructure de recherche
China Pharmaceutical University, State Administration of Traditional Chinese Medicine of the People's Republic of China et State Key Laboratory of Natural Medicines and School of Traditional Chinese Pharmacy, avec 1 autre affiliation.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.