Spontaneous rupture of hepatic metastasis as the initial presentation of gastric hepatoid adenocarcinoma: a rare case report and literature review
Rattachement africain : cn, tw. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Hepatoid adenocarcinoma (HAC) is an extremely rare and highly malignant tumor with histological features resembling hepatocellular carcinoma but originating from extrahepatic organs, most commonly in the stomach, known as gastric hepatoid adenocarcinoma (GHA). Spontaneous rupture of hepatic metastasis as the initial presentation of GHA is even rarer, posing significant challenges for clinical diagnosis and management. We present a case of a 74-year-old male admitted to the hospital for right upper abdomen pain. Through a combination of imaging, laboratory tests, interventional therapy, and pathological biopsy, the ultimate diagnosis was confirmed as GHA with spontaneous rupture of hepatic metastasis. The patient was transferred for chemotherapy and immunotherapy following transcatheter arterial embolization (TAE). We systematically reviewed relevant literature and summarized the clinical characteristics, diagnostic methods, treatment strategies, and prognosis of GHA with ruptured hepatic metastases. For patients with ruptured liver tumors, a comprehensive assessment of the potential primary site is essential to avoid misdiagnosis. TAE may create opportunities for subsequent curative surgery, chemotherapy, immunotherapy, and targeted therapy, potentially leading to an overall survival benefit. This case report aims to help clinicians gain a deeper understanding of this rare disease, thereby enabling early diagnosis and optimizing treatment strategies.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Spontaneous rupture of hepatic metastasis as the initial presentation of gastric hepatoid adenocarcinoma: a rare case report and literature review
- Date Crossref
- 02/02/2026
- Éditeur
- Frontiers Media SA
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Soochow University Department of Hepatobiliary Surgery pays non établi dans la noticeUniversité ou école supérieure
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Suzhou Traditional Chinese Medicine Hospital pays non établi dans la noticeÉtablissement de santé
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Xiyuan Hospital Department of Physical Medicine and Rehabilitation pays non établi dans la noticeÉtablissement de santé
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China Academy of Chinese Medical Sciences pays non établi dans la noticeUniversité ou école supérieure
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Suzhou Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Department of General Surgery pays non établi dans la noticeUniversité ou école supérieure
Department of Hepatobiliary Surgery — Soochow University, Suzhou Traditional Chinese Medicine Hospital et Department of Physical Medicine and Rehabilitation — Xiyuan Hospital, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.