Roles of children, isolation measures and socioeconomic status in SARS-CoV-2 household transmission: a retrospective cohort study in a southern US city
Rattachement africain : us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Objective: There has been significant debate about both the role of children in SARS-CoV-2 community transmission as well as the potential harm or lack thereof of the virus in the paediatric population. We aimed to better understand how children are impacted by a SARS-CoV-2 household infection and to identify behavioural and social factors related to infection. Methods: A cross-sectional study was conducted on households with children and a recent SARS-CoV-2 infection in Atlanta, GA. Participants were enrolled from December 2020 through November 2021. Salivary IgG against SARS-CoV-2 spike and nucleocapsid antigens was measured and household and infection data collected and analysed. Results: 49 households participated, including 121 adults and 57 children with 118 (66%) individuals having been infected with SARS-CoV-2. Mean SARS-CoV-2 secondary infection rate was 0.55 (95% CI 0.41 to 0.69) and median, 0.67 (range 0-1.0). Incidence rate did not differ significantly between households with paediatric versus adult index cases (incidence rate ratio (IRR) 0.97, 95% CI 0.63 to 1.49). However, sharing a bedroom or bathroom was associated with a higher incidence of secondary infection (IRR 2.36, 95% CI 1.49 to 3.74). Neighbourhood deprivation index was associated with higher household SARS-CoV-2 incidence, but this did not reach statistical significance. Conclusions: Child index cases appeared as likely to result in household secondary SARS-CoV-2 infections as adult index cases, while sharing rooms was associated with higher incidence of infection. This study highlights the importance of isolation measures to prevent household transmission of SARS-CoV-2 as well as counters common thought that children are less likely to transmit infection.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Roles of children, isolation measures and socioeconomic status in SARS-CoV-2 household transmission: a retrospective cohort study in a southern US city
- Date Crossref
- 01/01/2026
- Éditeur
- BMJ
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Emory University Department of Epidemiology pays non établi dans la noticeUniversité ou école supérieure
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Colorado Permanente Medical Group pays non établi dans la noticeÉtablissement de santé
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Children's Healthcare of Atlanta Center for Childhood Infections and Vaccines pays non établi dans la noticeÉtablissement de santé
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Johns Hopkins University pays non établi dans la noticeUniversité ou école supérieure
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Southeast Permanente Medical Group Inc Department of Quality and Patient Safety pays non établi dans la noticeEntreprise
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Johns Hopkins Bloomberg School of Public Health Department of Environmental Health and Engineering pays non établi dans la noticeUniversité ou école supérieure
Department of Epidemiology — Emory University, Colorado Permanente Medical Group et Center for Childhood Infections and Vaccines — Children's Healthcare of Atlanta, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.