Mutual learning for joint disease detection and severity prediction reveals multimodal pathogenesis for neurodegenerative disorders

Jin Zhang, Yong Ji, Jinhua Liu, Wenrui Cui, Xiaohui Yao, Hongdong Li, Daoqiang Zhang, Lei Du, Alzheimer’s Disease Neuroimaging Initiative, Michael W Weiner, Paul Aisen, Ronald Petersen, Clifford R Jack, William Jagust, Susan Landau, Monica Rivera-Mindt, Ozioma Okonkwo, Leslie M Shaw, Edward B Lee, Arthur W Toga, Laurel Beckett, Danielle Harvey, Robert C Green, Andrew J Saykin, Kwangsik Nho, Richard J Perrin, Duygu Tosun, Pallavi Sachdev, Erin Drake, Tom Montine, Cat Conti, Rachel Nosheny, Diana Truran, J Fockler, Melanie J Miller, Catherine (Cat) Conti, Winnie Kwang, Chengshi Jin, Adam Diaz, M. Ashford, Derek Flenniken, Adrienne Kormos, M. El Rafii, Rema Raman, Gustavo Jimenez, Michael Donohue, Jennifer Salazar, Andrea Fidell, Virginia Boatwright, Justin Robison, Caileigh Zimmerman, Yuliana Cabrera, Sarah Walter, Taylor Clanton, Elizabeth Shaffer, Caitlin Webb, Lindsey Hergesheimer, Stephanie Smith, Sheila Ogwang, Olusegun Adegoke, P. Mahboubi, Jeremy Pizzola, Cecily Jenkins, Naomi Saito, Kedir Adem Hussen, Hannatu Amaza, Mai Seng Thao, Shaniya Parkins Mt Sinai, Omobolanle Ayo, Matt Glittenberg, Isabella Hoang, Kaori Kubo Germano, Joe Strong, Trinity Weisensel, Fabiola Magana, Lisa Thomas, Vanessa Guzman, Adeyinka Ajayi, Joseph Di Benedetto, Sandra Talavera, Jr ,, Joel Felmlee, Nick C Fox, Paul Thompson, Charles DeCarli, Arvin Forghanian-Arani, Bret Borowski, Calvin Reyes, Caitie Hedberg, Chad Ward, Christopher Schwarz, Denise Reyes, Jeff Gunter, John Moore-Weiss, Kejal Kantarci, Leonard Matoush, Matthew Senjem, Prashanthi Vemuri, Robert Reid, Ian Malone, Sophia I Thomopoulos, Talia M Nir, N. Jahanshad, Alexander Knaack, Evan Fletcher, Duygu Tosun-Turgut, Stephanie Rossi Chen, Mark Choe, Karen Crawford, Paul A Yushkevich, Sandhitsu Das, Robert A Koeppe, Gil Rabinovici, Victor Villemagne, Brian LoPresti, John Morris, Erin Franklin, Haley Bernhardt, Nigel J Cairns, Lisa Taylor-Reinwald, Virginia M. Y. Lee, Magdalena Korecka, Magdalena Brylska, Yang Wan, J Q Trojanowki, Scott Neu, Tatiana M Foroud, Taeho Jo, Shannon L Risacher, Hannah Craft, Liana G Apostolova, Kelly Nudelman, Kelley Faber, Zoë Potter, K Lacy, Rima Kaddurah-Daouk, Li Shen, David Soleimani-Meigooni, Renaud La Joie, Konstantinos Chiotis, Maison Abu Raya, Agathe Vrillon, Charles Windon, Julien Lagarde, Zoe Lin, Aidyn Rose Hills, Jason Karlawish, Claire Erickson, Joshua Grill, E J Largent, K HARKINS, Leon Thal, Zaven Kachaturian, Richard Frank, Peter J Snyder, Neil Buckholtz, John K Hsiao, Laurie Ryan, Susan Molchan, Zaven Khachaturian, Maria Carrillo, William Potter, Lisa Laverne Barnes, Marie Bernard, Hector González, Carole Ho Denali, Jonathan Jackson, Eliezer Masliah, Donna Masterman, Richard Perrin, Nina Silverberg, Lisa Silbert, Jeffrey Kaye, Sylvia White (Salazar), Aimee Pierce, Amy Thomas, Tera Clay, Daniel Schwartz, Gillian Devereux, Janet "Janae" Taylor, Jennifer Ryan, Mike Nguyen, Madison DeCapo, Yanan Shang, Lon Schneider, Cynthia Munoz, Diana Ferman, Carlota Conant, Katherin Martin, Kristin Oleary, Sonia Pawluczyk, Elizabeth Trejo, Karen Dagerman, Liberty Teodoro, Mauricio Becerra, Madiha Fairooz, Sonia Garrison, Julia Boudreau, Y Castillo Avila, James Brewer, Aaron Jacobson, Antonio Gama, Chi Kim, Emily Little, Jennifer Frascino, Nichol Ferng, Socorro Trujillo, Judith Heidebrink, Steven MacDonald, Dariya Malyarenko, Jaimie Ziolkowski, James O’Connor, Nicole Robert, Suzan Lowe, Virginia Rogers, Barbara Hackenmiller, B. F. Boeve, Colleen Albers, Connie Kreuger, David Jones, David Knopman, Hugo Botha, Jessica Magnuson, Jonathan Graff-Radford, K Crawley, Michael Schumacher, S. McKinzie, Steven Smith, Tascha Helland, Val Lowe, Vijay Ramanan, Valory Pavlik, Jacob Faircloth, Jeffrey Bishop, J. Saketha Nath, Maria Chaudhary, Maria Kataki, Melissa Yu, Nathiel Pacini, Randall Barker, Regan Brooks, Ruchi Aggarwal, Lawrence Honig, Yaakov Stern, Akiva Mintz, Jonathan Cordona, Michelle Hernandez, Justin Long, Abbey Arnold, Alex Groves, Anna Middleton, Blake Vogler, Cierra McCurry, Connie Mayo, Cyrus A. Raji, Fatima S Amtashar, Heather Klemp, Heather Nicole, James Ruszkiewicz, Jasmina Kusuran, Jasmine Stewart, Jennifer Horenkamp, Julia Greeson, Kara Wever, Katie Vo, Kelly Larkin, Lesley K. Rao, Lisa Schoolcraft, Lora Gallagher, Madeline Paczynski, Maureen McMillan, Michael Holt, Nicole Gagliano, Rachel Henson, Renee LaBarge, Robert Swarm, Sarah Munie, Serena Cepeda, Stacey Winterton, Stephen Hegedus, TaNisha Wilson, Tanya Harte, Zach Bonacorsi, D. S Geldmacher, Amber Watkins, Brandi Barger, Bryan Smelser, Charna Bates, Cynthia Stover, E C McKinley, Gregory Ikner, Haley Hendrix, Harold Matthew Cooper, J. A. Mahaffey, Lindsey Booth Robbins, Loren Brown Ashley, Marissa Natelson-Love, Veronika Solomon, Hillel Grossman, Alexandra Groome, Allison Ardolino, Anthony Kaplan, Faye Sheppard, Genesis Burgos-Rivera, Gina Garcia-Camilo, Joanne Lim, Judith Neugroschl, Kimberly Jackson, Kirsten Evans, Laili Soleimani, Mary Sano, Nasrin Ghesani, Sarah Binder, Xiomara Mendoza Apuango, Ajay Sood, Amelia Troutman, Kimberly S. Blanchard, Arlene Richards,, Grace Nelson, K N Hendrickson, Erin Yurko, J. Plenge, Victoria Rufo, Raj Shah, R Duara, Brendan Lynch, Cesar Chirinos, Christine Dittrich, Debbie Campbell, Diego Mejia, Gilberto Perez, Helena Colvee, Joanna Gonzalez, Josalen Gondrez, J Knaack, Mara Acevedo, M J Cereijo, Maria T Greig-Custo, Michelle Villar, Morris Wishnia, Sheryl Detling, Warren W Barker, Marilyn Albert, Abhay Moghekar, Barbara Rodzon, Corey Demsky, G. Pontone, Jim J. Pekar, Leonie Farrington, Martin G. Pomper, Nicole Johnson, Tolulope Alo, M Sadowski, Anaztasia Ulysse, Arjun V. Masurkar, Brittany Marti, David Mossa, Emilie Geesey, Emily Petrocca, Evan T. Schulze, Jennifer Wong, Joseph Boonsiri, Sunnie Kenowsky, Tatianne Martinez, Veronica Briglall, P Murali Doraiswamy, Adaora Nwosu, Alisa Adhikari, Cammie Hellegers, J. Terry Petrella, Olga James, Terence Wong, Thomas C. Hawk, Sanjeev Vaishnavi, Hannah McCoubrey, Ilya M. Nasrallah, Rachel Rovere, Jeffrey Maneval, Elizabeth Robinson, Francisco Rivera, Jade Uffelman, Martha A. Combs, Patricia O’Donnell, Sara L. Manning, Richard King, Alayne Nieto, Amanda C. Glueck, Anjana Mandal, Audrie Swain, Bethanie Gamble, Beverly Meacham, Denece Forenback, Dorothy Ross, E Cheatham, Ellen Hartman, Gary Cornell, Jordan P. Harp, Laura Ashe, Laura Goins, Linda Watts, Morgan Yazell, Prabin Mandal, Regan Buckler, S.R. Vincent, Triana Rudd, Oscar Lopez, Ann Arlene Malia, Caitlin Chiado, Cary Zik, James Ruszkiewicz, K. E. Savage, Linda Fenice, MaryAnn Oakley, Paige C Tacey, Sarah Berman, S Bowser, S Hegedus, Xanthia Saganis, Anton Porsteinsson, Abigail Mathewson, Asa Widman, Bridget Holvey, Emily Clark, Esmeralda Morales, I.D. Young, Kevin Hopkins, Kimberly Martin, Nancy Kowalski, Rebecca Hunt, Roberta Calzavara, Russell Kurvach, Stephen D’Ambrosio, Gaby Thai, Beatriz Vides, Brigit Lieb, Catherine McAdams-Ortiz, Cyndy Toso, Ivan Mares, Kathryn Moorlach, Luter Liu, Maria Corona, Mary Nguyen, Melanie Tallakson, Michelle McDonnell, Milagros Rangel, Neetha Basheer, Patricia Place, Romina A. Romero, Steven Tam, Trung Nguyen, Abey Thomas, Alexander O. Frolov, Alka Khera, Amy Browning, Brendan Kelley, Courtney Dawson, Dana L. Mathews, Elaine Most, Elizeva Phillips, Lynn Nguyen, Maribel Nunez, Matalin Miller, Matthew R Jones, Natalie Martinez, Rebecca Logan, Roderick McColl, Sari Pham, Tiffani Fox, Tracey Moore, A. B. LEVEY, Abby Brown, Andrea Kippels, Ashton Ellison, Casie Lyons, Chadwick M. Hales, Cindy Parry, Courtney Williams, Elizabeth McCorkle, Guy Harris, Heather Rose, Inara Jooma, Jahmila Al-Amin, J. LAH, James Webster, Jessica Swiniarski, Latasha Chapman, Laura Donnelly, Lauren Mariotti, Mary Locke, Phyllis Vaughn, Rachael Penn, Sallie Carpentier, Samira Yeboah, Sarah Basadre, Sarah Malakauskas, Stefka Lyron, Tara Villinger, Terra Burney, Jeffrey Burns, Ala Abusalim, Alexandra Dahlgren, Alexandria Montero, Anne Arthur, Heather Dooly, Katelynn Kreszyn, Katherine Berner, Lindsey Gillen, Maria Scanlan, Mercedes Madison, N B Mathis, P. Switzer, Ryan Townley, Samantha Fikru, Samantha Sullivan, Ella Wright, Maryam Beigi, Anthony Daley, Ashley Ko, Brittney Luong, Glen Nyborg, Jessica Morales, Kelly A. Durbin, Lauren Garcia, Leila Parand, Lorena Macias, Lorena Monserratt, Maya Farchi, Pauline Wu, Robert Hernandez, Thao Rodriguez, Neill Graff-Radford, A’llana Marolt, Anton Thomas, Deborah Aloszka, Ercilia Moncayo, Erin Westerhold, Gregory Day, Kandise Chrestensen, Mary Imhansiemhonehi, Sanna McKinzie, Sochenda Stephens, Sylvia Grant, Jared R. Brosch, Amy Perkins, Aubree Saunders, Debra Silberberg Kovac, Heather Polson, Isabell Mwaura, Kassandra Mejia, Katherine Britt, Kathy King, Kayla Nichols, Kayley Lawrence, Lisa Rankin, M. W. Farlow, Patricia Wiesenauer, Robert Bryant, Scott Herring, Sheryl Lynch, Skylar Wilson, Traci Day, William Korst, Christopher van Dyck, Adam P. 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