Longitudinal home monitoring in interstitial lung disease: Report on 12-month data capture

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Introduction: Home spirometry can monitor forced vital capacity (FVC) in patients with interstitial lung disease (ILD) but the impact of continuous monitoring on oxygen saturation and health-related quality-of-life (HQoL) is not well understood. Aims and Objectives: To explore the relationships between home FVC (hFVC), pulse oximetry (SpO2) and patient-reported measures (PRMs) of symptoms and HQoL scores. Methods: A retrospective comparative analysis of a 12-month home monitoring programme. HQoL scores (EQ-5D-5L) were compared with hFVC and SpO2 measurements, modified Medical Research Council dyspnoea scale (mMRC), cough severity visual analogue scale (VAS), generalised anxiety disorder-7 (GAD-7) and patient health questionnaire-9 (PHQ-9) at baseline and 3-monthly intervals. Results: Data analysis included 147 patients who completed PRMs at least once at baseline and/or 3-monthly intervals. Strongly negative correlations were observed between EQ-5D-5L and mMRC, GAD-7 and PHQ-9 and between mMRC and predicted hFVC and SpO2. A positive correlation was observed between mMRC and cough severity VAS, GAD-7 and PHQ-9. This is demonstrated in figure 1. Figure 1. Spearman’s rank correlation coefficients erj;66/suppl_69/PA3020/F1 F1 F1 Conclusions: Home monitoring with a combination of spirometry, pulse oximetry and PRMs identifies clinical change. Optimising the choice and frequency of PRMs is a step closer to personalising care for patients with ILD.

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