Supplementary Figure S1 from Autocrine 17-β-Estradiol/Estrogen Receptor-α Loop Determines the Response to Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer
Le résumé fourni par la source
Outcome of non-small cell lung cancer patients, disaggregated according to gender, PD-L1 and ERα levels. Best response (PD: progressive disease; PR: partial response; SD: stable disease) after 6 months from the beginning of pembrolizumab treatment as first-line monotherapy, PFS and OS (Kapan-Meier and log-rank test) were analyzed in 35 NSCLC patients (15 females; 20 males). a-c. Female (F) and male (M) patients were stratified in CD274/PD-L1low and CD274/PD-L1high, according to the median value of the CD274/PD-L1mRNA, measured by RT-PCR in the tumor samples (technical triplicates). d-f. F and M patients were stratified in ESR1/ERαlow and ESR1/ERαhigh, according to the median value of the ESR1/ERα mRNA, measured by RT-PCR in the tumor samples (technical triplicates).
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Supplementary Figure S1 from Autocrine 17-β-Estradiol/Estrogen Receptor-α Loop Determines the Response to Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer
- Date Crossref
- 25/11/2025
- Éditeur
- American Association for Cancer Research (AACR)
- Type
- posted-content
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.