Impact of Atrial Fibrillation Type on Quality of Life and Clinical Parameters in Patients with Diabetes Mellitus
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Le résumé fourni par la source
Background: Atrial fibrillation (AF) is a prevalent condition with a major influence on patients’ quality of life, especially when blood glucose and heart rate are disrupted and systemic inflammation is present. Objective: This study aimed to compare Kansas City Cardiomyopathy Questionnaire (KCCQ) scores of diabetic patients by AF type and their correlations with different clinical and biological parameters. Material and methods: The retrospective study included 220 patients, from which only 200 were selected because of missing data. Patients were divided into three groups: paroxysmal AF (n = 49), persistent AF (n = 54), and permanent AF (n = 97). Demographic, clinical, and analytical data, echocardiographic parameters, heart rate, blood glucose, renal function, and inflammatory markers were compared between the three groups and their relationship with KCCQ scores. Results: The KCCQ score was significantly higher in patients with paroxysmal AF (69.50 ± 5.93), compared to persistent AF (56.92 ± 3.04) and permanent AF (42.28 ± 5.89), p < 0.001. In subanalyses, based on left ventricular ejection fraction (LVEF), the same trend was maintained, with lower KCCQ scores associated with more severe forms of AF. Significant negative correlations of the KCCQ score with blood glucose level (r = −0.2535, p = 0.0003), heart rate (r = −0.3071, p < 0.0001), and neutrophil–lymphocyte ratio (NLR) (r = −0.2395, p = 0.0006), and a positive correlation with glomerular filtration rate (GFR) (r = 0.4349, p < 0.0001) were identified. Conclusions: The type of atrial fibrillation significantly influences the quality of life assessed by the KCCQ score. Clinical and analytical parameters such as blood glucose, heart rate, systemic inflammation, and renal function significantly correlate with patients’ perception of health, indicating the importance of integrated management of AF.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Impact of Atrial Fibrillation Type on Quality of Life and Clinical Parameters in Patients with Diabetes Mellitus
- Date Crossref
- 21/11/2025
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Victor Babeș University of Medicine and Pharmacy Timișoara pays non établi dans la noticeUniversité ou école supérieure
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Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara pays non établi dans la noticeÉtablissement de santé
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Institute of Medical Ethics pays non établi dans la noticeOrganisation à but non lucratif
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“Victor Babes” University of Medicine and Pharmacy Department V pays non établi dans la noticeUniversité ou école supérieure
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University Clinic of Internal Medicine and Ambulatory Care Department VI-Cardiology pays non établi dans la noticeUniversité ou école supérieure
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General Medicine Faculty pays non établi dans la noticeUniversité ou école supérieure
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“Pius Brînzeu” Emergency County Hospital pays non établi dans la noticeÉtablissement de santé
Victor Babeș University of Medicine and Pharmacy Timișoara, Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara et Institute of Medical Ethics, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.