A Scoping Review of CERAMENT™ Applications in Orthopedic Surgery
Rattachement africain : it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Bone defects resulting from trauma, infection, or benign tumors pose major challenges in orthopedic surgery. Traditional approaches, such as autologous bone grafting, are limited by donor site morbidity and graft availability. CERAMENT™, a synthetic bone substitute composed of calcium sulfate and hydroxyapatite, offers an alternative with osteoconductive properties, controlled resorption, and injectability. Methods: A scoping review was conducted in accordance with PRISMA-ScR guidelines. Literature searches were performed in PubMed, Embase, and Scopus through 3 July 2025, using the terms “CERAMENT™” and “Orthopedics.” Studies were selected based on the PICO framework, focusing on clinical applications of CERAMENT™ in human orthopedic procedures. Results: Out of 480 initial records, 22 studies met the inclusion criteria. CERAMENT™ demonstrated favorable outcomes in a range of orthopedic settings. In the CERTiFy trial, it was non-inferior to autologous grafting in tibial plateau fractures. CERAMENT™ achieved full wound healing and bone remodeling in chronic osteomyelitis. Additional studies reported positive outcomes in tumor-related defect reconstruction, spinal augmentation, and foot and ankle surgery, highlighting reduced surgical morbidity and faster recovery. Conclusions: CERAMENT™ offers a versatile, effective solution for bone reconstruction across multiple orthopedic domains. Its clinical performance, ease of use, and antimicrobial capabilities support its integration into routine orthopedic practice. Further research may refine its indications and long-term benefits.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A Scoping Review of CERAMENT™ Applications in Orthopedic Surgery
- Date Crossref
- 22/10/2025
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Rome Tor Vergata pays non établi dans la noticeUniversité ou école supérieure
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University of Campania "Luigi Vanvitelli" Department of Medical and Surgical Specialties and Dentistry pays non établi dans la noticeUniversité ou école supérieure
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Unit of Orthopaedics and Traumatology pays non établi dans la noticeInstitution
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University of Tor Vergata Department of Clinical Sciences and Translational Medicine pays non établi dans la noticeUniversité ou école supérieure
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University of Campania “Luigi Vanvitelli” Department of Medical and Surgical Specialties and Dentistry pays non établi dans la noticeUniversité ou école supérieure
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Medifor pays non établi dans la noticeInstitution
University of Rome Tor Vergata, Department of Medical and Surgical Specialties and Dentistry — University of Campania "Luigi Vanvitelli" et Unit of Orthopaedics and Traumatology, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.