Traffic-related air pollutant exposure and physical performance in the Adult Changes in Thought cohort

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BACKGROUND: Declining physical function is common among older adults and is associated with reduced quality of life. There is little research on the relationship between air pollution and physical limitations, though exposure to air pollution is associated with many chronic conditions that lead to worsening physical function. This is especially true for several traffic-related air pollutants (TRAPs), as these pollutants can enter the circulatory system and lead to systemic inflammation. METHODS: , and UFPs of various size ranges) and physical performance assessed using a modified version of the Short Physical Performance Battery (score 0-12). This measure combines three physical functioning assessments: chair-stand time, gait speed, and grip strength. We used linear mixed models to understand whether pollutant exposure was associated with physical performance, both cross-sectionally at baseline and longitudinally after adjustment for other risk factors. RESULTS: exposure were suggestive of faster declines in physical performance (-0.046; 95 % CI: -0.096, 0.004) and (-0.032; 95 %CI: -0.074, 0.01), equivalent to an additional 2.6 months (-0.4, 5.6) and 1.8 months (-0.7, 4.3) of aging over 5 years, respectively. Higher UFP exposure was not associated with changes in physical performance over time. DISCUSSION: This work suggests that air pollution from traffic may impact the physical function of older adults, though more research is needed to confirm these findings.

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